North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management

Ali Alikhan; Christopher Sayed; Afsaneh Alavi; Raed Alhusayen; Alain Brassard; Craig Burkhart; Karen Crowell; Daniel B. Eisen; Alice B. Gottlieb; Iltefat Hamzavi; Paul G. Hazen; Tara Jaleel; Alexa B. Kimball; Joslyn Kirby; Michelle A. Lowes; Robert Micheletti; Angela Miller; Haley B. Naik; Dennis Orgill; Yves Poulin

doi:10.1016/j.jaad.2019.02.067

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management

Ali Alikhan, Christopher Sayed, Afsaneh Alavi, Raed Alhusayen, Alain Brassard, Craig Burkhart, Karen Crowell, Daniel B. Eisen, Alice B. Gottlieb, Iltefat Hamzavi, Paul G. Hazen, Tara Jaleel, Alexa B. Kimball, Joslyn Kirby, Michelle A. Lowes, Robert Micheletti, Angela Miller, Haley B. Naik, Dennis Orgill, Yves Poulin

Department of Dermatology

Research output: Contribution to journal › Article › peer-review

201 Scopus citations

Abstract

Hidradenitis suppurativa is a chronic inflammatory disorder affecting hair follicles, with profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and management of patients with hidradenitis suppurativa is still sparse in many areas, but it has grown substantially in the last decade. Part I of this evidence-based guideline is presented to support health care practitioners as they select optimal management strategies, including diagnostic testing, comorbidity screening, and both complementary and procedural treatment options. Recommendations and evidence grading based on the evidence available at the time of the review are provided.

Original language	English (US)
Pages (from-to)	76-90
Number of pages	15
Journal	Journal of the American Academy of Dermatology
Volume	81
Issue number	1
DOIs	https://doi.org/10.1016/j.jaad.2019.02.067
State	Published - Jul 2019

All Science Journal Classification (ASJC) codes

Dermatology

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10.1016/j.jaad.2019.02.067

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Alikhan, A., Sayed, C., Alavi, A., Alhusayen, R., Brassard, A., Burkhart, C., Crowell, K., Eisen, D. B., Gottlieb, A. B., Hamzavi, I., Hazen, P. G., Jaleel, T., Kimball, A. B., Kirby, J., Lowes, M. A., Micheletti, R., Miller, A., Naik, H. B., Orgill, D., & Poulin, Y. (2019). North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. Journal of the American Academy of Dermatology, 81(1), 76-90. https://doi.org/10.1016/j.jaad.2019.02.067

Alikhan, Ali ; Sayed, Christopher ; Alavi, Afsaneh et al. / North American clinical management guidelines for hidradenitis suppurativa : A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. In: Journal of the American Academy of Dermatology. 2019 ; Vol. 81, No. 1. pp. 76-90.

@article{8c1b7037e6f14a95b4ddaa2ea5a25912,

title = "North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management",

abstract = "Hidradenitis suppurativa is a chronic inflammatory disorder affecting hair follicles, with profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and management of patients with hidradenitis suppurativa is still sparse in many areas, but it has grown substantially in the last decade. Part I of this evidence-based guideline is presented to support health care practitioners as they select optimal management strategies, including diagnostic testing, comorbidity screening, and both complementary and procedural treatment options. Recommendations and evidence grading based on the evidence available at the time of the review are provided.",

author = "Ali Alikhan and Christopher Sayed and Afsaneh Alavi and Raed Alhusayen and Alain Brassard and Craig Burkhart and Karen Crowell and Eisen, {Daniel B.} and Gottlieb, {Alice B.} and Iltefat Hamzavi and Hazen, {Paul G.} and Tara Jaleel and Kimball, {Alexa B.} and Joslyn Kirby and Lowes, {Michelle A.} and Robert Micheletti and Angela Miller and Naik, {Haley B.} and Dennis Orgill and Yves Poulin",

note = "Funding Information: Disclosure: Dr Sayed reports service as a speaker for AbbVie and Novartis, an advisory board member for AbbVie and InflaRx, a coinvestigator for AbbVie and Novartis, and an investigator for InflaR and UCB. Dr Hamzavi reports service as an investigator for AbbVie, The Microdermis Corporation, Adelphi Values, and Lenicura and a consultant for UCB and Incyte; in addition, he is president of the Hidradenitis Suppurativa Foundation. Dr Hazen reports service as a speaker for AbbVie and an advisory board member for AbbVie. Dr Kimball reports service as a consultant and investigator for Amgen, AbbVie, Janssen, and Novartis and has received fellowship funding from Novarti and AbbVie. Dr Lowes reports service as an advisory board member for AbbVie and Janssen and a consultant for AbbVie, XBiotech, and Incyte. Dr Alavi reports service as a clinical investigator and consultant for AbbVie, Janssen, Novartis, Pfizer, Galderma, Leo, and Valeant and has received grant funding from AbbVie. Dr Naik reports grant funding from AbbVie. Dr Alhusayen reports service for AbbVie as an advisory board member and consulting and has received research funding from the company; he has also served as an advisory board member for Janssen and a consultant for Eli Lilly and Company and Hidramed Solutions. Dr Orgill has served as a consultant and investigator for KCI, Inc, and Integra. Dr Brassard has served as a speaker and advisory board member for AbbVie, Janssen, Celgene, and 3M and as a speaker for Coloplast and Hollister. Dr Miller has served as a consultant for AbbVie and an advisory board member for AbbVie and BSN; in addition, she is employed by the Hidradenitis Suppurativa Foundation and is president and founding director of the Hope for HS support group. Dr Poulin has served as an investigator, advisory board member, and speaker for AbbVie. Dr Kirby has served as an advisory board member and speaker for AbbVie and a consultant for Incyte and Chemocentryx. Dr Gottlieb has served as an investigator for Novartis and a speaker for AbbVie. Dr Jaleel has served as an investigator for Eli Lilly and Company. Dr Alikhan, Dr Micheletti, Dr Eisen, Dr Burkhart, and Dr Crowell have no conflicts of interest to disclose. Funding sources: None. Disclosure: Dr Sayed reports service as a speaker for AbbVie and Novartis, an advisory board member for AbbVie and InflaRx, a coinvestigator for AbbVie and Novartis, and an investigator for InflaR and UCB. Dr Hamzavi reports service as an investigator for AbbVie, The Microdermis Corporation, Adelphi Values, and Lenicura and a consultant for UCB and Incyte; in addition, he is president of the Hidradenitis Suppurativa Foundation. Dr Hazen reports service as a speaker for AbbVie and an advisory board member for AbbVie. Dr Kimball reports service as a consultant and investigator for Amgen, AbbVie, Janssen, and Novartis and has received fellowship funding from Novarti and AbbVie. Dr Lowes reports service as an advisory board member for AbbVie and Janssen and a consultant for AbbVie, XBiotech, and Incyte. Dr Alavi reports service as a clinical investigator and consultant for AbbVie, Janssen, Novartis, Pfizer, Galderma, Leo, and Valeant and has received grant funding from AbbVie. Dr Naik reports grant funding from AbbVie. Dr Alhusayen reports service for AbbVie as an advisory board member and consulting and has received research funding from the company; he has also served as an advisory board member for Janssen and a consultant for Eli Lilly and Company and Hidramed Solutions. Dr Orgill has served as a consultant and investigator for KCI, Inc, and Integra. Dr Brassard has served as a speaker and advisory board member for AbbVie, Janssen, Celgene, and 3M and as a speaker for Coloplast and Hollister. Dr Miller has served as a consultant for AbbVie and an advisory board member for AbbVie and BSN; in addition, she is employed by the Hidradenitis Suppurativa Foundation and is president and founding director of the Hope for HS support group. Dr Poulin has served as an investigator, advisory board member, and speaker for AbbVie. Dr Kirby has served as an advisory board member and speaker for AbbVie and a consultant for Incyte and Chemocentryx. Dr Gottlieb has served as an investigator for Novartis and a speaker for AbbVie. Dr Jaleel has served as an investigator for Eli Lilly and Company. Dr Alikhan, Dr Micheletti, Dr Eisen, Dr Burkhart, and Dr Crowell have no conflicts of interest to disclose. The committee would like to thank the external reviewers who provided valuable feedback, including Dr Wayne Gulliver, Dr Errol Prens, and Dr Hessel van der Zee. Funding sources: None. Disclosure: Dr Sayed reports service as a speaker for AbbVie and Novartis, an advisory board member for AbbVie and InflaRx, a coinvestigator for AbbVie and Novartis, and an investigator for InflaR and UCB. Dr Hamzavi reports service as an investigator for AbbVie, The Microdermis Corporation, Adelphi Values, and Lenicura and a consultant for UCB and Incyte; in addition, he is president of the Hidradenitis Suppurativa Foundation. Dr Hazen reports service as a speaker for AbbVie and an advisory board member for AbbVie. Dr Kimball reports service as a consultant and investigator for Amgen, AbbVie, Janssen, and Novartis and has received fellowship funding from Novarti and AbbVie. Dr Lowes reports service as an advisory board member for AbbVie and Janssen and a consultant for AbbVie, XBiotech, and Incyte. Dr Alavi reports service as a clinical investigator and consultant for AbbVie, Janssen, Novartis, Pfizer, Galderma, Leo, and Valeant and has received grant funding from AbbVie. Dr Naik reports grant funding from AbbVie. Dr Alhusayen reports service for AbbVie as an advisory board member and consulting and has received research funding from the company; he has also served as an advisory board member for Janssen and a consultant for Eli Lilly and Company and Hidramed Solutions. Dr Orgill has served as a consultant and investigator for KCI, Inc, and Integra. Dr Brassard has served as a speaker and advisory board member for AbbVie, Janssen, Celgene, and 3M and as a speaker for Coloplast and Hollister. Dr Miller has served as a consultant for AbbVie and an advisory board member for AbbVie and BSN; in addition, she is employed by the Hidradenitis Suppurativa Foundation and is president and founding director of the Hope for HS support group. Dr Poulin has served as an investigator, advisory board member, and speaker for AbbVie. Dr Kirby has served as an advisory board member and speaker for AbbVie and a consultant for Incyte and Chemocentryx. Dr Gottlieb has served as an investigator for Novartis and a speaker for AbbVie. Dr Jaleel has served as an investigator for Eli Lilly and Company. Dr Alikhan, Dr Micheletti, Dr Eisen, Dr Burkhart, and Dr Crowell have no conflicts of interest to disclose. Publisher Copyright: {\textcopyright} 2019 American Academy of Dermatology, Inc.",

year = "2019",

month = jul,

doi = "10.1016/j.jaad.2019.02.067",

language = "English (US)",

volume = "81",

pages = "76--90",

journal = "Journal of the American Academy of Dermatology",

issn = "0190-9622",

publisher = "Mosby Inc.",

number = "1",

}

Alikhan, A, Sayed, C, Alavi, A, Alhusayen, R, Brassard, A, Burkhart, C, Crowell, K, Eisen, DB, Gottlieb, AB, Hamzavi, I, Hazen, PG, Jaleel, T, Kimball, AB, Kirby, J, Lowes, MA, Micheletti, R, Miller, A, Naik, HB, Orgill, D & Poulin, Y 2019, 'North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management', Journal of the American Academy of Dermatology, vol. 81, no. 1, pp. 76-90. https://doi.org/10.1016/j.jaad.2019.02.067

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. / Alikhan, Ali; Sayed, Christopher; Alavi, Afsaneh et al.
In: Journal of the American Academy of Dermatology, Vol. 81, No. 1, 07.2019, p. 76-90.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - North American clinical management guidelines for hidradenitis suppurativa

T2 - A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management

AU - Alikhan, Ali

AU - Sayed, Christopher

AU - Alavi, Afsaneh

AU - Alhusayen, Raed

AU - Brassard, Alain

AU - Burkhart, Craig

AU - Crowell, Karen

AU - Eisen, Daniel B.

AU - Gottlieb, Alice B.

AU - Hamzavi, Iltefat

AU - Hazen, Paul G.

AU - Jaleel, Tara

AU - Kimball, Alexa B.

AU - Kirby, Joslyn

AU - Lowes, Michelle A.

AU - Micheletti, Robert

AU - Miller, Angela

AU - Naik, Haley B.

AU - Orgill, Dennis

AU - Poulin, Yves

N1 - Funding Information: Disclosure: Dr Sayed reports service as a speaker for AbbVie and Novartis, an advisory board member for AbbVie and InflaRx, a coinvestigator for AbbVie and Novartis, and an investigator for InflaR and UCB. Dr Hamzavi reports service as an investigator for AbbVie, The Microdermis Corporation, Adelphi Values, and Lenicura and a consultant for UCB and Incyte; in addition, he is president of the Hidradenitis Suppurativa Foundation. Dr Hazen reports service as a speaker for AbbVie and an advisory board member for AbbVie. Dr Kimball reports service as a consultant and investigator for Amgen, AbbVie, Janssen, and Novartis and has received fellowship funding from Novarti and AbbVie. Dr Lowes reports service as an advisory board member for AbbVie and Janssen and a consultant for AbbVie, XBiotech, and Incyte. Dr Alavi reports service as a clinical investigator and consultant for AbbVie, Janssen, Novartis, Pfizer, Galderma, Leo, and Valeant and has received grant funding from AbbVie. Dr Naik reports grant funding from AbbVie. Dr Alhusayen reports service for AbbVie as an advisory board member and consulting and has received research funding from the company; he has also served as an advisory board member for Janssen and a consultant for Eli Lilly and Company and Hidramed Solutions. Dr Orgill has served as a consultant and investigator for KCI, Inc, and Integra. Dr Brassard has served as a speaker and advisory board member for AbbVie, Janssen, Celgene, and 3M and as a speaker for Coloplast and Hollister. Dr Miller has served as a consultant for AbbVie and an advisory board member for AbbVie and BSN; in addition, she is employed by the Hidradenitis Suppurativa Foundation and is president and founding director of the Hope for HS support group. Dr Poulin has served as an investigator, advisory board member, and speaker for AbbVie. Dr Kirby has served as an advisory board member and speaker for AbbVie and a consultant for Incyte and Chemocentryx. Dr Gottlieb has served as an investigator for Novartis and a speaker for AbbVie. Dr Jaleel has served as an investigator for Eli Lilly and Company. Dr Alikhan, Dr Micheletti, Dr Eisen, Dr Burkhart, and Dr Crowell have no conflicts of interest to disclose. Funding sources: None. Disclosure: Dr Sayed reports service as a speaker for AbbVie and Novartis, an advisory board member for AbbVie and InflaRx, a coinvestigator for AbbVie and Novartis, and an investigator for InflaR and UCB. Dr Hamzavi reports service as an investigator for AbbVie, The Microdermis Corporation, Adelphi Values, and Lenicura and a consultant for UCB and Incyte; in addition, he is president of the Hidradenitis Suppurativa Foundation. Dr Hazen reports service as a speaker for AbbVie and an advisory board member for AbbVie. Dr Kimball reports service as a consultant and investigator for Amgen, AbbVie, Janssen, and Novartis and has received fellowship funding from Novarti and AbbVie. Dr Lowes reports service as an advisory board member for AbbVie and Janssen and a consultant for AbbVie, XBiotech, and Incyte. Dr Alavi reports service as a clinical investigator and consultant for AbbVie, Janssen, Novartis, Pfizer, Galderma, Leo, and Valeant and has received grant funding from AbbVie. Dr Naik reports grant funding from AbbVie. Dr Alhusayen reports service for AbbVie as an advisory board member and consulting and has received research funding from the company; he has also served as an advisory board member for Janssen and a consultant for Eli Lilly and Company and Hidramed Solutions. Dr Orgill has served as a consultant and investigator for KCI, Inc, and Integra. Dr Brassard has served as a speaker and advisory board member for AbbVie, Janssen, Celgene, and 3M and as a speaker for Coloplast and Hollister. Dr Miller has served as a consultant for AbbVie and an advisory board member for AbbVie and BSN; in addition, she is employed by the Hidradenitis Suppurativa Foundation and is president and founding director of the Hope for HS support group. Dr Poulin has served as an investigator, advisory board member, and speaker for AbbVie. Dr Kirby has served as an advisory board member and speaker for AbbVie and a consultant for Incyte and Chemocentryx. Dr Gottlieb has served as an investigator for Novartis and a speaker for AbbVie. Dr Jaleel has served as an investigator for Eli Lilly and Company. Dr Alikhan, Dr Micheletti, Dr Eisen, Dr Burkhart, and Dr Crowell have no conflicts of interest to disclose. The committee would like to thank the external reviewers who provided valuable feedback, including Dr Wayne Gulliver, Dr Errol Prens, and Dr Hessel van der Zee. Funding sources: None. Disclosure: Dr Sayed reports service as a speaker for AbbVie and Novartis, an advisory board member for AbbVie and InflaRx, a coinvestigator for AbbVie and Novartis, and an investigator for InflaR and UCB. Dr Hamzavi reports service as an investigator for AbbVie, The Microdermis Corporation, Adelphi Values, and Lenicura and a consultant for UCB and Incyte; in addition, he is president of the Hidradenitis Suppurativa Foundation. Dr Hazen reports service as a speaker for AbbVie and an advisory board member for AbbVie. Dr Kimball reports service as a consultant and investigator for Amgen, AbbVie, Janssen, and Novartis and has received fellowship funding from Novarti and AbbVie. Dr Lowes reports service as an advisory board member for AbbVie and Janssen and a consultant for AbbVie, XBiotech, and Incyte. Dr Alavi reports service as a clinical investigator and consultant for AbbVie, Janssen, Novartis, Pfizer, Galderma, Leo, and Valeant and has received grant funding from AbbVie. Dr Naik reports grant funding from AbbVie. Dr Alhusayen reports service for AbbVie as an advisory board member and consulting and has received research funding from the company; he has also served as an advisory board member for Janssen and a consultant for Eli Lilly and Company and Hidramed Solutions. Dr Orgill has served as a consultant and investigator for KCI, Inc, and Integra. Dr Brassard has served as a speaker and advisory board member for AbbVie, Janssen, Celgene, and 3M and as a speaker for Coloplast and Hollister. Dr Miller has served as a consultant for AbbVie and an advisory board member for AbbVie and BSN; in addition, she is employed by the Hidradenitis Suppurativa Foundation and is president and founding director of the Hope for HS support group. Dr Poulin has served as an investigator, advisory board member, and speaker for AbbVie. Dr Kirby has served as an advisory board member and speaker for AbbVie and a consultant for Incyte and Chemocentryx. Dr Gottlieb has served as an investigator for Novartis and a speaker for AbbVie. Dr Jaleel has served as an investigator for Eli Lilly and Company. Dr Alikhan, Dr Micheletti, Dr Eisen, Dr Burkhart, and Dr Crowell have no conflicts of interest to disclose. Publisher Copyright: © 2019 American Academy of Dermatology, Inc.

PY - 2019/7

Y1 - 2019/7

N2 - Hidradenitis suppurativa is a chronic inflammatory disorder affecting hair follicles, with profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and management of patients with hidradenitis suppurativa is still sparse in many areas, but it has grown substantially in the last decade. Part I of this evidence-based guideline is presented to support health care practitioners as they select optimal management strategies, including diagnostic testing, comorbidity screening, and both complementary and procedural treatment options. Recommendations and evidence grading based on the evidence available at the time of the review are provided.

AB - Hidradenitis suppurativa is a chronic inflammatory disorder affecting hair follicles, with profoundly negative impact on patient quality of life. Evidence informing ideal evaluation and management of patients with hidradenitis suppurativa is still sparse in many areas, but it has grown substantially in the last decade. Part I of this evidence-based guideline is presented to support health care practitioners as they select optimal management strategies, including diagnostic testing, comorbidity screening, and both complementary and procedural treatment options. Recommendations and evidence grading based on the evidence available at the time of the review are provided.

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UR - http://www.scopus.com/inward/citedby.url?scp=85065339304&partnerID=8YFLogxK

U2 - 10.1016/j.jaad.2019.02.067

DO - 10.1016/j.jaad.2019.02.067

M3 - Article

C2 - 30872156

AN - SCOPUS:85065339304

SN - 0190-9622

VL - 81

SP - 76

EP - 90

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

IS - 1

ER -

Alikhan A, Sayed C, Alavi A, Alhusayen R, Brassard A, Burkhart C et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management. Journal of the American Academy of Dermatology. 2019 Jul;81(1):76-90. doi: 10.1016/j.jaad.2019.02.067

North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part I: Diagnosis, evaluation, and the use of complementary and procedural management

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