Novel biomaterial for bone tissue engineering

S. Lakshmi, J. D. Bender, Y. E. Greish, P. W. Brown, H. R. Allcock, C. T. Laurencin

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A novel biomaterial was developed by blending poly(lactide-co-glycolide) (PLAGA) with poly[bis(ethyl alanato) phosphazene] (PNEA) as candidate material for bone tissue engineering. The molecular weight of the polymer was determined by gel permeation chromatography (GPC). Primary rat osteoblast adhesion and proliferation on two dimensional (2D) matrices of polymers and blends were quantitatively followed using a colorimetric assay and qualitatively by scanning electron microscopy (SEM). The phenotypic expression of the cells on the blends was significantly higher than the cells on polyphosphazene.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

All Science Journal Classification (ASJC) codes

  • General Engineering


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