Nuclear role of WASp in the pathogenesis of dysregulated T_H1 immunity in human Wiskott-Aldrich syndrome

Keyphrases

• T Helper 1 100%
• Dysregulated 100%
• Wiskott-Aldrich Syndrome 100%
• TBX21 50%
• Regulatory Genes 30%
• Proximal Promoter 30%
• Chromatin 20%
• T Helper Cells 20%
• T-bet 20%
• Protein Expression 10%
• Transcriptional Regulation 10%
• Genetic Mapping 10%
• In Vitro Activity 10%
• Autoimmune Disease 10%
• RNA Interference 10%
• Derangement 10%
• Gene Regulatory Network 10%
• GATA3 10%
• Messenger RNA Expression 10%
• Enzymatic Activity 10%
• X-linked 10%
• T Helper 17 (Th17) 10%
• Core Promoter 10%
• Clinical Symptomatology 10%
• H3K9me3 10%
• Adaptive Immunity 10%
• Retinoblastoma Protein 10%
• Protein S Deficiency 10%
• 2A Protein 10%
• Th2 Immunity 10%
• Histone Methylation 10%
• Wiskott-Aldrich Syndrome Protein 10%
• Epigenetic Control 10%
• Cell Fate Decision 10%
• Filamentous Actin (F-actin) 10%
• H3K36me3 10%
• H3K4me3 10%
• Chromatin Dynamics 10%
• Jumonji Domain 10%

Biochemistry, Genetics and Molecular Biology

• Promoter Region 100%
• TBX21 100%
• Locus Control Region 50%
• Transcription 33%
• Dynamics 33%
• Protein Expression 16%
• Epigenetics 16%
• Binding Protein 16%
• Enzyme Activity 16%
• Cell Fate 16%
• Retinoblastoma 16%
• GATA3 16%
• Adaptive Immunity 16%
• Histone Methylation 16%
• Wiskott-Aldrich Syndrome Protein 16%
• RNAI 16%
• Gene Regulatory Network 16%
• Filamentous Actin 16%

Immunology and Microbiology

• Wiskott-Aldrich Syndrome 100%
• Promoter Region 37%
• TBX21 37%
• Regulator Gene 18%
• Dynamics 12%
• T Helper 1 Cell 12%
• Protein Binding 6%
• Adaptive Immune System 6%
• Autoimmune Disease 6%
• Transcription Factor GATA 3 6%
• Protein Expression 6%
• Cell Fate 6%
• Enzyme Activity 6%
• Histone Methylation 6%
• Combined Immunodeficiencies 6%
• RNAI 6%
• Filamentous Actin 6%
• Gene Regulatory Network 6%