Number-controlled spatial arrangement of gold nanoparticles with DNA dendrimers

Ping Chen, Tao Zhang, Tao Zhou, Dongsheng Liu

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


In this study we described a controlled self-assembly of gold nanoparticles mediated by DNA dendrimers. Stepwise titration of three-arm Y-shaped DNA monomers through a divergent route can assemble different generations of DNA dendrimers with discrete DNA sticky ends on the surface. Hybridizing gold nanoparticles bearing one single-stranded DNA to different generations of DNA dendrimers thereby results in assembly of number-controlled discrete gold nanoparticle groupings. The conjugation strategy used herein provides a novel model for spatial positioning of functionalized nanoparticles and precise construction of multivalent nanomaterials.

Original languageEnglish (US)
Pages (from-to)70553-70556
Number of pages4
JournalRSC Advances
Issue number74
StatePublished - 2016

All Science Journal Classification (ASJC) codes

  • General Chemistry
  • General Chemical Engineering


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