Obesity and sleep disturbances

Jacqueline Danisi; Fernandez-Mendoza Julio Fernandez-Mendoza; Alexandros N. Vgontzas; Edward O. Bixler

doi:10.1016/B978-0-12-816430-3.00007-5

Obesity and sleep disturbances

Jacqueline Danisi, Fernandez-Mendoza Julio Fernandez-Mendoza, Alexandros N. Vgontzas, Edward O. Bixler

Research output: Chapter in Book/Report/Conference proceeding › Chapter

6 Scopus citations

Abstract

The global obesity epidemic is rising due to unmodifiable and modifiable causes, one of them being inadequate sleep. Although shortened sleep duration and poor sleep have been shown to lead to a greater incidence of obesity, nonobese chronic insomniacs do not follow this trend. This reveals that not all types of inadequate sleep lead to weight gain and onset of subsequent obesity. In addition, OSA patients are shown to gain weight, even after using continuous positive airway pressure. Obesity is the main risk factor for OSA, which aids in its progression due to the increase in the accumulation of higher plasma proinflammatory load. This increase in proinflammatory cytokines plays a role in the development of adverse cardiometabolic outcomes. In turn, this metabolic dysregulation may lead to the development of daytime sleepiness.

Original language	English (US)
Title of host publication	The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle
Publisher	Elsevier
Pages	123-142
Number of pages	20
ISBN (Electronic)	9780128164303
DOIs	https://doi.org/10.1016/B978-0-12-816430-3.00007-5
State	Published - Jan 1 2019

All Science Journal Classification (ASJC) codes

General Medicine
General Neuroscience

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-12-816430-3.00007-5

Cite this

@inbook{8f4d9635c23344dbb8090a1832360265,

title = "Obesity and sleep disturbances",

abstract = "The global obesity epidemic is rising due to unmodifiable and modifiable causes, one of them being inadequate sleep. Although shortened sleep duration and poor sleep have been shown to lead to a greater incidence of obesity, nonobese chronic insomniacs do not follow this trend. This reveals that not all types of inadequate sleep lead to weight gain and onset of subsequent obesity. In addition, OSA patients are shown to gain weight, even after using continuous positive airway pressure. Obesity is the main risk factor for OSA, which aids in its progression due to the increase in the accumulation of higher plasma proinflammatory load. This increase in proinflammatory cytokines plays a role in the development of adverse cardiometabolic outcomes. In turn, this metabolic dysregulation may lead to the development of daytime sleepiness.",

author = "Jacqueline Danisi and {Julio Fernandez-Mendoza}, Fernandez-Mendoza and Vgontzas, {Alexandros N.} and Bixler, {Edward O.}",

year = "2019",

month = jan,

day = "1",

doi = "10.1016/B978-0-12-816430-3.00007-5",

language = "English (US)",

pages = "123--142",

booktitle = "The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle",

publisher = "Elsevier",

address = "Netherlands",

}

TY - CHAP

T1 - Obesity and sleep disturbances

AU - Danisi, Jacqueline

AU - Julio Fernandez-Mendoza, Fernandez-Mendoza

AU - Vgontzas, Alexandros N.

AU - Bixler, Edward O.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - The global obesity epidemic is rising due to unmodifiable and modifiable causes, one of them being inadequate sleep. Although shortened sleep duration and poor sleep have been shown to lead to a greater incidence of obesity, nonobese chronic insomniacs do not follow this trend. This reveals that not all types of inadequate sleep lead to weight gain and onset of subsequent obesity. In addition, OSA patients are shown to gain weight, even after using continuous positive airway pressure. Obesity is the main risk factor for OSA, which aids in its progression due to the increase in the accumulation of higher plasma proinflammatory load. This increase in proinflammatory cytokines plays a role in the development of adverse cardiometabolic outcomes. In turn, this metabolic dysregulation may lead to the development of daytime sleepiness.

AB - The global obesity epidemic is rising due to unmodifiable and modifiable causes, one of them being inadequate sleep. Although shortened sleep duration and poor sleep have been shown to lead to a greater incidence of obesity, nonobese chronic insomniacs do not follow this trend. This reveals that not all types of inadequate sleep lead to weight gain and onset of subsequent obesity. In addition, OSA patients are shown to gain weight, even after using continuous positive airway pressure. Obesity is the main risk factor for OSA, which aids in its progression due to the increase in the accumulation of higher plasma proinflammatory load. This increase in proinflammatory cytokines plays a role in the development of adverse cardiometabolic outcomes. In turn, this metabolic dysregulation may lead to the development of daytime sleepiness.

UR - http://www.scopus.com/inward/record.url?scp=85077323578&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85077323578&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-816430-3.00007-5

DO - 10.1016/B978-0-12-816430-3.00007-5

M3 - Chapter

AN - SCOPUS:85077323578

SP - 123

EP - 142

BT - The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle

PB - Elsevier

ER -

Obesity and sleep disturbances

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this