TY - JOUR
T1 - Ocular metastasis of colorectal cancer
T2 - An uncommon presentation of a common malignancy
AU - Khawaja, Muhammad Rizwan
AU - Minturn, John T.
AU - Spittler, A. John
AU - Chiorean, E. Gabriela
N1 - Publisher Copyright:
© 2015 King Faisal Specialist Hospital & Research Centre.
PY - 2015
Y1 - 2015
N2 - Approximately 20% of patients with colorectal cancer have metastatic disease at time of diagnosis, and another 25-35% develop metastases during the course of their disease. Liver, peritoneum, and lungs are the most common sites of metastases. We report the case of a 60-year-old female who presented with ocular metastasis 4 years after her initial curative-intent treatment for T3N1M0 rectal adenocarcinoma. After local eye radiation therapy, she received palliative systemic chemotherapy and enjoyed a good quality of life for 32 months before succumbing to progressive disease. Ocular metastasis of colorectal cancer is rare. When present, it usually occurs in the setting of diffuse hematogenous spread. In addition to local therapy, systemic chemotherapy should also be considered.
AB - Approximately 20% of patients with colorectal cancer have metastatic disease at time of diagnosis, and another 25-35% develop metastases during the course of their disease. Liver, peritoneum, and lungs are the most common sites of metastases. We report the case of a 60-year-old female who presented with ocular metastasis 4 years after her initial curative-intent treatment for T3N1M0 rectal adenocarcinoma. After local eye radiation therapy, she received palliative systemic chemotherapy and enjoyed a good quality of life for 32 months before succumbing to progressive disease. Ocular metastasis of colorectal cancer is rare. When present, it usually occurs in the setting of diffuse hematogenous spread. In addition to local therapy, systemic chemotherapy should also be considered.
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U2 - 10.1016/j.hemonc.2015.02.002
DO - 10.1016/j.hemonc.2015.02.002
M3 - Article
C2 - 25784129
AN - SCOPUS:84925850778
SN - 1658-3876
VL - 8
SP - 176
EP - 180
JO - Hematology/ Oncology and Stem Cell Therapy
JF - Hematology/ Oncology and Stem Cell Therapy
IS - 4
ER -