Off-design considerations of the 50cc Penn State Ventricular Assist Device

Leslie A. Oley, Keefe B. Manning, Arnold A. Fontaine, Steven Deutsch

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Particle image velocimetry is used to study the flow field associated with off-design conditions of the 50cc Penn State Ventricular Assist Device. Phase average data, for 300 consecutive beats, was acquired for 60, 75, and 90 beats per minute (bpm) at 35/65 systolic duration and at 75 bpm for 50/50 systolic duration. Diastolic flow is dominated by the inflow jet and shows more penetration and better wall washing at higher beat rates and shorter diastolic time. A flow separation near the minor orifice of the aortic valve, however, is larger under these conditions. Turbulent energy, which peaks during diastole, is found to be strongest at the edges of the jet and near the valves and scales well with the maximum inlet jet velocity. A region of potential separation on the right lateral wall is identified and will be relieved by geometric modifications of the evolving design.

Original languageEnglish (US)
Pages (from-to)378-386
Number of pages9
JournalArtificial organs
Issue number5
StatePublished - May 2005

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Medicine (miscellaneous)
  • Biomaterials
  • Biomedical Engineering


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