Olfactory dysfunction in man: Anatomical and behavioral aspects

Paul J. Eslinger, Antonio R. Damasio, Gary W. Van Hoesen

Research output: Contribution to journalArticlepeer-review

102 Scopus citations


We reviewed studies examining the olfaction of patients with brain damage for the purpose of discerning correlations between disordered structure and function. Patient samples included those with neurological disorders and neurosurgical interventions and recording of spontaneous or elicited neuronal activity. Brain areas involved in olfaction include the olfactory bulbs, the orbitofrontal and medial temporal cortices, the thalamus, and the amygdala. Despite recent advances in olfactory anatomy, understanding of how these structures are related to olfactory detection, discrimination, and recognition continues to be limited. Inadequate localization of brain lesions and lack of comprehensive behavioral assessment have thus far prevented a detailed account of the organization of olfaction in the human brain.

Original languageEnglish (US)
Pages (from-to)259-285
Number of pages27
JournalBrain and cognition
Issue number3
StatePublished - Jul 1982

All Science Journal Classification (ASJC) codes

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)
  • Cognitive Neuroscience


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