On-chip single nanoparticle detection and sizing by mode splitting in an ultrahigh-Q microresonator

Jiangang Zhu, Sahin Kaya Ozdemir, Yun Feng Xiao, Lin Li, Lina He, Da Ren Chen, Lan Yang

Research output: Contribution to journalArticlepeer-review

997 Scopus citations


The ability to detect and size individual nanoparticles with high resolution is crucial to understanding the behaviour of single particles and effectively using their strong size-dependent properties to develop innovative products. We report real-time, in situ detection and sizing of single nanoparticles, down to 30nm in radius, using mode splitting in a monolithic ultrahigh-quality-factor (Q) whispering-gallery-mode microresonator. Particle binding splits a whispering-gallery mode into two spectrally shifted resonance modes, forming a self-referenced detection scheme. This technique provides superior noise suppression and enables the extraction of accurate particle size information with a single-shot measurement in a microscale device. Our method requires neither labelling of the particles nor a priori information on their presence in the medium, providing an effective platform to study nanoparticles at single-particle resolution.

Original languageEnglish (US)
Pages (from-to)46-49
Number of pages4
JournalNature Photonics
Issue number1
StatePublished - Jan 2010

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics


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