ORAI calcium channels

Mohamed Trebak; James W. Putney

doi:10.1152/physiol.00011.2017

ORAI calcium channels

Mohamed Trebak, James W. Putney

Research output: Contribution to journal › Review article › peer-review

80 Scopus citations

Abstract

In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on downstream cellular signaling controlling important physiological functions.

Original language	English (US)
Pages (from-to)	332-342
Number of pages	11
Journal	Physiology
Volume	32
Issue number	4
DOIs	https://doi.org/10.1152/physiol.00011.2017
State	Published - Jun 14 2017

All Science Journal Classification (ASJC) codes

Physiology

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10.1152/physiol.00011.2017

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title = "ORAI calcium channels",

abstract = "In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on downstream cellular signaling controlling important physiological functions.",

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AU - Putney, James W.

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AB - In this review article, we discuss the different gene products and translational variants of ORAI proteins and their contribution to the makeup of different native calcium-conducting channels with distinct compositions and modes of activation. We also review the different modes of regulation of these distinct calcium channels and their impact on downstream cellular signaling controlling important physiological functions.

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ORAI calcium channels

Abstract

All Science Journal Classification (ASJC) codes

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