TY - JOUR
T1 - Organ space infection following ileocolectomy for Crohn's disease
T2 - A National Surgical Quality Improvement Project study
AU - Wilson, Matthew Z.
AU - Connelly, Tara M.
AU - Hollenbeak, Christopher S.
AU - Messaris, Evangelos
N1 - Publisher Copyright:
© 2014 Elsevier Inc. All rights reserved.
PY - 2014/11/1
Y1 - 2014/11/1
N2 - Background Organ space infection (OSI) rates post ileocolectomy for Crohn's disease are relatively high. The aim of this study was to determine which factors predispose to OSI in this patient cohort.Methods Data for 2,618 Crohn's patients undergoing ileocolectomy between 2005 and 2011 were obtained from the American College of Surgeons National Surgical Quality Improvement Project database. Primary outcome was an OSI within 30 days of discharge. Univariate analysis using chi-square and Student t tests and a logistic multivariate analysis were performed. .Results Preoperative weight loss (odds ratio [OR] 2.11, P =.002), extended operating time (OR 1.57, P =.016), open procedures (OR 1.47, P =.043), and contaminated/dirty wounds (OR 1.95, P =.008) conferred an increased risk for OSI on multivariate analysis. Rates of stoma creation and steroid use were not significantly different between the groups.Conclusions Weight loss is a preoperative, potentially modifiable variable associated with OSI in Crohn's patients undergoing ileocolectomy and OSI-Associated operative factors which may be noted to identify high-risk patients include extended operating time and open procedures.
AB - Background Organ space infection (OSI) rates post ileocolectomy for Crohn's disease are relatively high. The aim of this study was to determine which factors predispose to OSI in this patient cohort.Methods Data for 2,618 Crohn's patients undergoing ileocolectomy between 2005 and 2011 were obtained from the American College of Surgeons National Surgical Quality Improvement Project database. Primary outcome was an OSI within 30 days of discharge. Univariate analysis using chi-square and Student t tests and a logistic multivariate analysis were performed. .Results Preoperative weight loss (odds ratio [OR] 2.11, P =.002), extended operating time (OR 1.57, P =.016), open procedures (OR 1.47, P =.043), and contaminated/dirty wounds (OR 1.95, P =.008) conferred an increased risk for OSI on multivariate analysis. Rates of stoma creation and steroid use were not significantly different between the groups.Conclusions Weight loss is a preoperative, potentially modifiable variable associated with OSI in Crohn's patients undergoing ileocolectomy and OSI-Associated operative factors which may be noted to identify high-risk patients include extended operating time and open procedures.
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U2 - 10.1016/j.amjsurg.2014.04.010
DO - 10.1016/j.amjsurg.2014.04.010
M3 - Article
C2 - 25096262
AN - SCOPUS:84911441009
SN - 0002-9610
VL - 208
SP - 749
EP - 755
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 5
ER -