Organic Photoredox-Catalyzed Cycloadditions under Single-Chain Polymer Confinement

Jacob J. Piane, Lauren E. Chamberlain, Steven Huss, Lucas T. Alameda, Ashley C. Hoover, Elizabeth Elacqua

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Cooperative catalysis enables synthetic transformations that are not feasible using monocatalytic systems. Such reactions are often diffusion controlled and require multiple catalyst interactions at high dilution. We developed a confined dual-catalytic polymer nanoreactor that enforces catalyst colocalization to enhance reactivity in a fully homogeneous system. The photoredox-catalyzed dimerization of substituted styrenes is disclosed using confined-single-chain polymers bearing triarylpyrylium-based pendants, with pyrene as an electron relay catalyst. Enhanced reactivity with low catalyst loadings was observed compared to monocatalytic polymers with small-molecule additives and analogous small molecules. Our approach realizes a dual-catalytic single-chain polymer that provides enhanced reactivity under confinement, presenting a further approach for diffusion-limited-photoredox catalysis.

Original languageEnglish (US)
Pages (from-to)13251-13256
Number of pages6
JournalACS Catalysis
Issue number22
StatePublished - Nov 20 2020

All Science Journal Classification (ASJC) codes

  • Catalysis
  • General Chemistry


Dive into the research topics of 'Organic Photoredox-Catalyzed Cycloadditions under Single-Chain Polymer Confinement'. Together they form a unique fingerprint.

Cite this