Abstract
Dendritic cells (DCs) have been extensively studied in mice lymphoid organs, but less is known about the origin and the mechanisms that regulate DC development and function in non-lymphoid tissues. Here, we discuss recent evidence establishing the contribution of the DC-restricted lineage to the non-lymphoid tissue DC pool and discuss the mechanisms that control the homeostasis of non-lymphoid tissue DCs. We also review recent results underlining the functional specialization of tissue DCs and discuss the potential implications of these findings in tissue immunity and in the development of novel vaccine strategies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 55-75 |
| Number of pages | 21 |
| Journal | Immunological Reviews |
| Volume | 234 |
| Issue number | 1 |
| DOIs | |
| State | Published - Mar 2010 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology
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