Osteoid osteomas: A pain in the night diagnosis

Nancy Laurence, Monica Epelman, Richard I. Markowitz, Camilo Jaimes, Diego Jaramillo, Nancy A. Chauvin

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


Osteoid osteoma is a common benign boneforming lesion that is composed of a nidus of vascular osteoid tissue and woven bone lined by osteoblasts. It is frequently associated with considerable surrounding inflammation. The diagnosis is usually straightforward when imaging reveals a radiolucent nidus surrounded by variable degrees of reactive sclerosis. However, the diagnosis can be elusive when osteoid osteomas occur in atypical locations, as they may have a nonspecific and misleading appearance on different imaging modalities, particularly on MRI. The purpose of this pictorial essay is to review the typical and atypical features of osteoid osteomas on different imaging modalities, and the appearance of osteoid osteomas in different locations. We also review growth disturbances caused by osteoid osteomas and potential mimickers, with imaging characteristics that can aid in diagnosis.

Original languageEnglish (US)
Pages (from-to)1490-1501
Number of pages12
JournalPediatric Radiology
Issue number12
StatePublished - Dec 2012

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging


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