Over-expression of Ubiquitin carboxy terminal hydrolase-L1 induces apoptosis in breast cancer cells

Keyphrases

• Breast Cancer Cells 100%
• Overexpression 100%
• Induced Apoptosis 100%
• UCHL1 100%
• MCF-7 41%
• Apoptosis 25%
• Tumor Cells 16%
• Deubiquitination 16%
• Flow Cytometry 8%
• Plasmid 8%
• Small Interfering RNA (siRNA) 8%
• Western Blot 8%
• Phosphoinositide 3-kinase (PI3K) 8%
• B-cell Lymphoma 2 (Bcl-2) 8%
• MCF-7 Cells 8%
• Signaling Molecules 8%
• Retinal Cells 8%
• Carcinoma Cell Lines 8%
• Bcl-xL 8%
• Ubiquitin 8%
• MTT Assay 8%
• Cytochrome c (Cyt c) 8%
• Tumor Therapy 8%
• Opposite Effects 8%
• Ubiquitination 8%
• Murine Double Minute 2 (MDM2) 8%
• Protease Family 8%
• Phospho-Akt 8%
• Multidrug Resistance 8%
• Protein Conjugates 8%
• 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide 8%
• Active caspase-3 8%
• PcDNA3.1 8%
• Hoechst 33258 Staining 8%
• Testicular Germ Cells 8%
• Human Breast Carcinoma Cells 8%
• FasL 8%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Ubiquitin 16%
• Plasmid 8%
• Mouse 8%
• Western Blot 8%
• Proteasome 8%
• Phosphoinositide 3-Kinase 8%
• Small Interfering RNA 8%
• P21 8%
• Protease 8%
• P53 8%
• Caspase 3 8%
• Ubiquitination 8%
• Deubiquitination 8%
• Flow Cytometry 8%
• Bcl-2 8%
• Conjugate 8%
• Cytochrome C 8%
• Bcl-xL 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Ubiquitin Thiolesterase 100%
• 4 [5 (4 Methyl 1 piperazinyl)[2,5' Bi 1h Benzimidazol] 2' Yl]phenol 8%
• 3 (4,5 Dimethyl 2 Thiazolyl) 2,5 Diphenyltetrazolium Bromide 8%