Abstract
p16INK4A (hereafter called p16) is a faithful cellular ally in the fight against tumorigenesis. Although its canonical pathway through retinoblastoma (RB) is well delineated, RB-independent functions for p16 are beginning to emerge. Here we summarize non-canonical roles of p16, including our recent finding on its role in nucleotide metabolism.
| Original language | English (US) |
|---|---|
| Article number | e1677140 |
| Journal | Molecular and Cellular Oncology |
| Volume | 6 |
| Issue number | 6 |
| DOIs | |
| State | Published - Nov 2 2019 |
All Science Journal Classification (ASJC) codes
- Molecular Medicine
- Cancer Research