Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America

Pavel Flegontov; N. Ezgi Altınışık; Piya Changmai; Nadin Rohland; Swapan Mallick; Nicole Adamski; Deborah A. Bolnick; Nasreen Broomandkhoshbacht; Francesca Candilio; Brendan J. Culleton; Olga Flegontova; T. Max Friesen; Choongwon Jeong; Thomas K. Harper; Denise Keating; Douglas J. Kennett; Alexander M. Kim; Thiseas C. Lamnidis; Ann Marie Lawson; Iñigo Olalde; Jonas Oppenheimer; Ben A. Potter; Jennifer Raff; Robert A. Sattler; Pontus Skoglund; Kristin Stewardson; Edward J. Vajda; Sergey Vasilyev; Elizaveta Veselovskaya; M. Geoffrey Hayes; Dennis H. O’Rourke; Johannes Krause; Ron Pinhasi; David Reich; Stephan Schiffels

doi:10.1038/s41586-019-1251-y

Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America

Pavel Flegontov, N. Ezgi Altınışık, Piya Changmai, Nadin Rohland, Swapan Mallick, Nicole Adamski, Deborah A. Bolnick, Nasreen Broomandkhoshbacht, Francesca Candilio, Brendan J. Culleton, Olga Flegontova, T. Max Friesen, Choongwon Jeong, Thomas K. Harper, Denise Keating, Douglas J. Kennett, Alexander M. Kim, Thiseas C. Lamnidis, Ann Marie Lawson, Iñigo OlaldeJonas Oppenheimer, Ben A. Potter, Jennifer Raff, Robert A. Sattler, Pontus Skoglund, Kristin Stewardson, Edward J. Vajda, Sergey Vasilyev, Elizaveta Veselovskaya, M. Geoffrey Hayes, Dennis H. O’Rourke, Johannes Krause, Ron Pinhasi, David Reich, Stephan Schiffels

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

Abstract

Much of the American Arctic was first settled 5,000 years ago, by groups of people known as Palaeo-Eskimos. They were subsequently joined and largely displaced around 1,000 years ago by ancestors of the present-day Inuit and Yup’ik^1–3. The genetic relationship between Palaeo-Eskimos and Native American, Inuit, Yup’ik and Aleut populations remains uncertain^4–6. Here we present genomic data for 48 ancient individuals from Chukotka, East Siberia, the Aleutian Islands, Alaska, and the Canadian Arctic. We co-analyse these data with data from present-day Alaskan Iñupiat and West Siberian populations and published genomes. Using methods based on rare-allele and haplotype sharing, as well as established techniques^4,7–9, we show that Palaeo-Eskimo-related ancestry is ubiquitous among people who speak Na-Dene and Eskimo–Aleut languages. We develop a comprehensive model for the Holocene peopling events of Chukotka and North America, and show that Na-Dene-speaking peoples, people of the Aleutian Islands, and Yup’ik and Inuit across the Arctic region all share ancestry from a single Palaeo-Eskimo-related Siberian source.

Original language	English (US)
Pages (from-to)	236-240
Number of pages	5
Journal	Nature
Volume	570
Issue number	7760
DOIs	https://doi.org/10.1038/s41586-019-1251-y
State	Published - Jun 13 2019

All Science Journal Classification (ASJC) codes

General

Access to Document

10.1038/s41586-019-1251-y

Cite this

Flegontov, P., Altınışık, N. E., Changmai, P., Rohland, N., Mallick, S., Adamski, N., Bolnick, D. A., Broomandkhoshbacht, N., Candilio, F., Culleton, B. J., Flegontova, O., Friesen, T. M., Jeong, C., Harper, T. K., Keating, D., Kennett, D. J., Kim, A. M., Lamnidis, T. C., Lawson, A. M., ... Schiffels, S. (2019). Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America. Nature, 570(7760), 236-240. https://doi.org/10.1038/s41586-019-1251-y

@article{7085cc1dd8924cd6a62b7f3584e9c498,

title = "Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America",

abstract = "Much of the American Arctic was first settled 5,000 years ago, by groups of people known as Palaeo-Eskimos. They were subsequently joined and largely displaced around 1,000 years ago by ancestors of the present-day Inuit and Yup{\textquoteright}ik1–3. The genetic relationship between Palaeo-Eskimos and Native American, Inuit, Yup{\textquoteright}ik and Aleut populations remains uncertain4–6. Here we present genomic data for 48 ancient individuals from Chukotka, East Siberia, the Aleutian Islands, Alaska, and the Canadian Arctic. We co-analyse these data with data from present-day Alaskan I{\~n}upiat and West Siberian populations and published genomes. Using methods based on rare-allele and haplotype sharing, as well as established techniques4,7–9, we show that Palaeo-Eskimo-related ancestry is ubiquitous among people who speak Na-Dene and Eskimo–Aleut languages. We develop a comprehensive model for the Holocene peopling events of Chukotka and North America, and show that Na-Dene-speaking peoples, people of the Aleutian Islands, and Yup{\textquoteright}ik and Inuit across the Arctic region all share ancestry from a single Palaeo-Eskimo-related Siberian source.",

author = "Pavel Flegontov and Altını{\c s}ık, {N. Ezgi} and Piya Changmai and Nadin Rohland and Swapan Mallick and Nicole Adamski and Bolnick, {Deborah A.} and Nasreen Broomandkhoshbacht and Francesca Candilio and Culleton, {Brendan J.} and Olga Flegontova and Friesen, {T. Max} and Choongwon Jeong and Harper, {Thomas K.} and Denise Keating and Kennett, {Douglas J.} and Kim, {Alexander M.} and Lamnidis, {Thiseas C.} and Lawson, {Ann Marie} and I{\~n}igo Olalde and Jonas Oppenheimer and Potter, {Ben A.} and Jennifer Raff and Sattler, {Robert A.} and Pontus Skoglund and Kristin Stewardson and Vajda, {Edward J.} and Sergey Vasilyev and Elizaveta Veselovskaya and Hayes, {M. Geoffrey} and O{\textquoteright}Rourke, {Dennis H.} and Johannes Krause and Ron Pinhasi and David Reich and Stephan Schiffels",

note = "Publisher Copyright: {\textcopyright} 2019, The Author(s), under exclusive licence to Springer Nature Limited.",

year = "2019",

month = jun,

day = "13",

doi = "10.1038/s41586-019-1251-y",

language = "English (US)",

volume = "570",

pages = "236--240",

journal = "Nature",

issn = "0028-0836",

publisher = "Nature Research",

number = "7760",

}

Flegontov, P, Altınışık, NE, Changmai, P, Rohland, N, Mallick, S, Adamski, N, Bolnick, DA, Broomandkhoshbacht, N, Candilio, F, Culleton, BJ, Flegontova, O, Friesen, TM, Jeong, C, Harper, TK, Keating, D, Kennett, DJ, Kim, AM, Lamnidis, TC, Lawson, AM, Olalde, I, Oppenheimer, J, Potter, BA, Raff, J, Sattler, RA, Skoglund, P, Stewardson, K, Vajda, EJ, Vasilyev, S, Veselovskaya, E, Hayes, MG, O’Rourke, DH, Krause, J, Pinhasi, R, Reich, D & Schiffels, S 2019, 'Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America', Nature, vol. 570, no. 7760, pp. 236-240. https://doi.org/10.1038/s41586-019-1251-y

TY - JOUR

T1 - Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America

AU - Flegontov, Pavel

AU - Altınışık, N. Ezgi

AU - Changmai, Piya

AU - Rohland, Nadin

AU - Mallick, Swapan

AU - Adamski, Nicole

AU - Bolnick, Deborah A.

AU - Broomandkhoshbacht, Nasreen

AU - Candilio, Francesca

AU - Culleton, Brendan J.

AU - Flegontova, Olga

AU - Friesen, T. Max

AU - Jeong, Choongwon

AU - Harper, Thomas K.

AU - Keating, Denise

AU - Kennett, Douglas J.

AU - Kim, Alexander M.

AU - Lamnidis, Thiseas C.

AU - Lawson, Ann Marie

AU - Olalde, Iñigo

AU - Oppenheimer, Jonas

AU - Potter, Ben A.

AU - Raff, Jennifer

AU - Sattler, Robert A.

AU - Skoglund, Pontus

AU - Stewardson, Kristin

AU - Vajda, Edward J.

AU - Vasilyev, Sergey

AU - Veselovskaya, Elizaveta

AU - Hayes, M. Geoffrey

AU - O’Rourke, Dennis H.

AU - Krause, Johannes

AU - Pinhasi, Ron

AU - Reich, David

AU - Schiffels, Stephan

PY - 2019/6/13

Y1 - 2019/6/13

N2 - Much of the American Arctic was first settled 5,000 years ago, by groups of people known as Palaeo-Eskimos. They were subsequently joined and largely displaced around 1,000 years ago by ancestors of the present-day Inuit and Yup’ik1–3. The genetic relationship between Palaeo-Eskimos and Native American, Inuit, Yup’ik and Aleut populations remains uncertain4–6. Here we present genomic data for 48 ancient individuals from Chukotka, East Siberia, the Aleutian Islands, Alaska, and the Canadian Arctic. We co-analyse these data with data from present-day Alaskan Iñupiat and West Siberian populations and published genomes. Using methods based on rare-allele and haplotype sharing, as well as established techniques4,7–9, we show that Palaeo-Eskimo-related ancestry is ubiquitous among people who speak Na-Dene and Eskimo–Aleut languages. We develop a comprehensive model for the Holocene peopling events of Chukotka and North America, and show that Na-Dene-speaking peoples, people of the Aleutian Islands, and Yup’ik and Inuit across the Arctic region all share ancestry from a single Palaeo-Eskimo-related Siberian source.

AB - Much of the American Arctic was first settled 5,000 years ago, by groups of people known as Palaeo-Eskimos. They were subsequently joined and largely displaced around 1,000 years ago by ancestors of the present-day Inuit and Yup’ik1–3. The genetic relationship between Palaeo-Eskimos and Native American, Inuit, Yup’ik and Aleut populations remains uncertain4–6. Here we present genomic data for 48 ancient individuals from Chukotka, East Siberia, the Aleutian Islands, Alaska, and the Canadian Arctic. We co-analyse these data with data from present-day Alaskan Iñupiat and West Siberian populations and published genomes. Using methods based on rare-allele and haplotype sharing, as well as established techniques4,7–9, we show that Palaeo-Eskimo-related ancestry is ubiquitous among people who speak Na-Dene and Eskimo–Aleut languages. We develop a comprehensive model for the Holocene peopling events of Chukotka and North America, and show that Na-Dene-speaking peoples, people of the Aleutian Islands, and Yup’ik and Inuit across the Arctic region all share ancestry from a single Palaeo-Eskimo-related Siberian source.

UR - http://www.scopus.com/inward/record.url?scp=85067075462&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85067075462&partnerID=8YFLogxK

U2 - 10.1038/s41586-019-1251-y

DO - 10.1038/s41586-019-1251-y

M3 - Article

C2 - 31168094

AN - SCOPUS:85067075462

SN - 0028-0836

VL - 570

SP - 236

EP - 240

JO - Nature

JF - Nature

IS - 7760

ER -

Palaeo-Eskimo genetic ancestry and the peopling of Chukotka and North America

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this