Pancytopenia induced by aminoglutethimide in the treatment of breast cancer

B. Lawrence, R. J. Santen, A. Lipton, H. A. Harvey, R. Hamilton, T. Mercurio

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Aminoglutethimide is an investigational agent of proven benefit in the treatment of metastatic breast carcinoma. We report herein a case of aminoglutethimide-induced pancytopenia complicated by bleeding and gram-negative septicemia. Severe pancytopenia is a rare but important side effect of this new drug and is rapidly reversible when the agent is withdrawn.

Original languageEnglish (US)
Pages (from-to)1581-1583
Number of pages3
JournalCancer Treatment Reports
Volume62
Issue number10
StatePublished - 1978

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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