TY - JOUR
T1 - Path perturbation detection tasks reduce MSTd neuronal self-movement heading responses
AU - Page, William K.
AU - Duffy, Charles J.
N1 - Funding Information:
This work was supported by National Eye Institute Grants R01-EY022062 and Office of Naval Research Grant N000141110525.
Funding Information:
After postoperative recovery, the monkeys were returned to their home cage where monitoring guided the administration of Banamine (1 mg/kg im) analgesia under veterinary supervision. The excised scalp edge and recording chambers were gently debrided and wiped with betadine daily. All protocols were approved by the University of Rochester Committee on Animal Research and complied with U.S. Public Health Service and Society for Neuroscience policy on the care of laboratory animals.
Publisher Copyright:
© 2018 American Physiological Society. All rights reserved.
PY - 2018/1
Y1 - 2018/1
N2 - We presented optic flow and real movement heading stimuli while recording MSTd neuronal activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow heading perturbations, vestibular detection of real movement heading perturbations, and auditory detection of brief tones. Push-button RTs were fastest for tones and slower for visual and vestibular heading perturbations, suggesting that the tone detection task was easier. Neuronal heading selectivity was strongest during the tone detection task, and weaker during the visual and vestibular heading perturbation detection tasks. Heading selectivity was weaker during visual and vestibular path perturbation detection, despite our presented heading cues only in the visual and vestibular modalities. We conclude that focusing on the self-movement transients of path perturbation distracted the monkeys from their heading and reduced neuronal responsiveness to heading direction. NEW & NOTEWORTHY Heading analysis is critical for steering and navigation. We recorded the activity of monkey cortical heading neurons during naturalistic self-movement. When the monkeys were required to respond to transient changes in their path, neuronal responses to heading direction were diminished. This suggests that the need to respond to momentary path perturbations reduces your ability to process your heading direction.
AB - We presented optic flow and real movement heading stimuli while recording MSTd neuronal activity. Monkeys were alternately engaged in three tasks: visual detection of optic flow heading perturbations, vestibular detection of real movement heading perturbations, and auditory detection of brief tones. Push-button RTs were fastest for tones and slower for visual and vestibular heading perturbations, suggesting that the tone detection task was easier. Neuronal heading selectivity was strongest during the tone detection task, and weaker during the visual and vestibular heading perturbation detection tasks. Heading selectivity was weaker during visual and vestibular path perturbation detection, despite our presented heading cues only in the visual and vestibular modalities. We conclude that focusing on the self-movement transients of path perturbation distracted the monkeys from their heading and reduced neuronal responsiveness to heading direction. NEW & NOTEWORTHY Heading analysis is critical for steering and navigation. We recorded the activity of monkey cortical heading neurons during naturalistic self-movement. When the monkeys were required to respond to transient changes in their path, neuronal responses to heading direction were diminished. This suggests that the need to respond to momentary path perturbations reduces your ability to process your heading direction.
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U2 - 10.1152/jn.00958.2016
DO - 10.1152/jn.00958.2016
M3 - Article
C2 - 29046430
AN - SCOPUS:85043450205
SN - 0022-3077
VL - 119
SP - 124
EP - 133
JO - Journal of neurophysiology
JF - Journal of neurophysiology
IS - 1
ER -