PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates

Medicine & Life Sciences

• Insulin Receptor Substrate Proteins 100%
• Platelet-Derived Growth Factor 89%
• Insulin Receptor 86%
• Vascular Smooth Muscle 75%
• Smooth Muscle Myocytes 67%
• Cell Proliferation 50%
• Phosphorylation 23%
• serine receptor 16%
• Down-Regulation 13%
• Insulin 9%
• Serine 9%
• PI103 8%
• PDGF receptor tyrosine kinase 8%
• lactacystin 7%
• Phosphoinositide-3 Kinase Inhibitors 6%
• Platelet-Derived Growth Factor Receptors 6%
• U 0126 6%
• Imatinib Mesylate 5%
• TOR Serine-Threonine Kinases 5%
• Sirolimus 5%
• Phosphatidylinositol 3-Kinase 4%
• Insulin-Like Growth Factor I 4%
• Protein Kinases 4%
• Protein Isoforms 3%
• Pharmacology 3%
• Growth 2%
• Therapeutics 1%