Pediatric Cardiopulmonary Bypass: Does Perfusion Mode Matter?

Jonathan J. Talor, Akif Ündar

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


This current review describes how components of the cardiopulmonary bypass (CPB) circuit are selected and examines the benefits of pulsatile perfusion for use during CPB. Pulsatile flow generates significantly greater surplus hemodynamic energy (SHE) than nonpulsatile flow; higher SHE values have been associated with better microcirculation perfusion, lower rates of systemic inflammatory response, and better vital organ protection. Pulsatile perfusion may have a positive effect on clinical outcomes, play a role in preserving homeostasis, and help to decrease morbidity associated with CPB.

Original languageEnglish (US)
Pages (from-to)296-300
Number of pages5
JournalWorld Journal for Pediatric and Congenital Heart Surgery
Issue number2
StatePublished - Apr 2011

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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