Pediatric mixed‐phenotype acute leukemia: What’s new?

Sandeep Batra; Anthony John Ross

doi:10.3390/cancers13184658

Pediatric mixed‐phenotype acute leukemia: What’s new?

Sandeep Batra
, Anthony John Ross

Department of Pediatrics

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Mixed‐phenotype acute leukemias (MPAL) are rare in children and often lack consensus on optimal management. This review examines the current controversies and emerging paradigms in the management of pediatric MPAL. We examine risk stratification, outcomes of recent retrospective and prospective collaborative trials, and the role of transplantation and precision genomics, and outline emerging targets and concepts in this rare entity.

Original language	English (US)
Article number	4658
Journal	Cancers
Volume	13
Issue number	18
DOIs	https://doi.org/10.3390/cancers13184658
State	Published - Sep 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Oncology
Cancer Research

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10.3390/cancers13184658

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title = "Pediatric mixed‐phenotype acute leukemia: What{\textquoteright}s new?",

abstract = "Mixed‐phenotype acute leukemias (MPAL) are rare in children and often lack consensus on optimal management. This review examines the current controversies and emerging paradigms in the management of pediatric MPAL. We examine risk stratification, outcomes of recent retrospective and prospective collaborative trials, and the role of transplantation and precision genomics, and outline emerging targets and concepts in this rare entity.",

author = "Sandeep Batra and Ross, \{Anthony John\}",

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year = "2021",

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language = "English (US)",

volume = "13",

journal = "Cancers",

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T1 - Pediatric mixed‐phenotype acute leukemia

T2 - What’s new?

AU - Batra, Sandeep

AU - Ross, Anthony John

PY - 2021/9

Y1 - 2021/9

N2 - Mixed‐phenotype acute leukemias (MPAL) are rare in children and often lack consensus on optimal management. This review examines the current controversies and emerging paradigms in the management of pediatric MPAL. We examine risk stratification, outcomes of recent retrospective and prospective collaborative trials, and the role of transplantation and precision genomics, and outline emerging targets and concepts in this rare entity.

AB - Mixed‐phenotype acute leukemias (MPAL) are rare in children and often lack consensus on optimal management. This review examines the current controversies and emerging paradigms in the management of pediatric MPAL. We examine risk stratification, outcomes of recent retrospective and prospective collaborative trials, and the role of transplantation and precision genomics, and outline emerging targets and concepts in this rare entity.

UR - https://www.scopus.com/pages/publications/85114949711

UR - https://www.scopus.com/pages/publications/85114949711#tab=citedBy

U2 - 10.3390/cancers13184658

DO - 10.3390/cancers13184658

M3 - Review article

AN - SCOPUS:85114949711

SN - 2072-6694

VL - 13

JO - Cancers

JF - Cancers

IS - 18

M1 - 4658

ER -

Pediatric mixed‐phenotype acute leukemia: What’s new?

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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