Peptide map analysis of mutant transplantation antigens

Sandra J. Ewald; Jan Klein; Leroy E. Hood

doi:10.1007/BF01561464

Peptide map analysis of mutant transplantation antigens

Sandra J. Ewald, Jan Klein, Leroy E. Hood

Biology

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13 Scopus citations

Abstract

H-2K antigens from two histocompatibility mutants, M506 (H-2K^fa) and M523 (H-2K^ka) and from their parental strains, A.CA (H-2k^f) and CBA (H-2K^k), are compared by ion exchange chromatography of tryptic peptides. Both mutant molecules differ from their parental counterparts by only one or two peptides. These results are discussed with reference to the alterations in serological and biological properties exhibited by the two mutations.

Original language	English (US)
Pages (from-to)	551-559
Number of pages	9
Journal	Immunogenetics
Volume	8
Issue number	1
DOIs	https://doi.org/10.1007/BF01561464
State	Published - Dec 1979

All Science Journal Classification (ASJC) codes

Immunology
Genetics

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10.1007/BF01561464

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title = "Peptide map analysis of mutant transplantation antigens",

abstract = "H-2K antigens from two histocompatibility mutants, M506 (H-2Kfa) and M523 (H-2Kka) and from their parental strains, A.CA (H-2kf) and CBA (H-2Kk), are compared by ion exchange chromatography of tryptic peptides. Both mutant molecules differ from their parental counterparts by only one or two peptides. These results are discussed with reference to the alterations in serological and biological properties exhibited by the two mutations.",

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year = "1979",

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AU - Ewald, Sandra J.

AU - Klein, Jan

AU - Hood, Leroy E.

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AB - H-2K antigens from two histocompatibility mutants, M506 (H-2Kfa) and M523 (H-2Kka) and from their parental strains, A.CA (H-2kf) and CBA (H-2Kk), are compared by ion exchange chromatography of tryptic peptides. Both mutant molecules differ from their parental counterparts by only one or two peptides. These results are discussed with reference to the alterations in serological and biological properties exhibited by the two mutations.

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Peptide map analysis of mutant transplantation antigens

Abstract

All Science Journal Classification (ASJC) codes

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