TY - JOUR
T1 - Pericardial-fluid complement. Normal values
AU - Kinney, E.
AU - Wynn, J.
AU - Hinton, D. M.
AU - Demers, L.
AU - O'Neill, M.
AU - Parr, G.
AU - Ward, S.
AU - Zelis, R.
PY - 1979
Y1 - 1979
N2 - Reports of low pericardial-fluid complement levels in systemic lupus erythematosus and rheumatoid arthritis have been difficult to interpret, as few data are available to describe complement concentrations in patients without pericardial disease. The authors therefore determined normal values under standardized conditions of collection, storage, and assay. The normal ranges for pericardial-fluid C3, C4, and total hemolytic complement were 35-127 mg/dl, 6.3-23 mg/dl, and 1.9-9.1 CH50 units, respectively. Storage at -20 C resulted in a 50% reduction in values. Hence, storage at -70 C is recommended. As the level of pericardial-fluid total hemolytic complement is normally low, caution is needed in interpreting its apparent reduction in various immunologic diseases.
AB - Reports of low pericardial-fluid complement levels in systemic lupus erythematosus and rheumatoid arthritis have been difficult to interpret, as few data are available to describe complement concentrations in patients without pericardial disease. The authors therefore determined normal values under standardized conditions of collection, storage, and assay. The normal ranges for pericardial-fluid C3, C4, and total hemolytic complement were 35-127 mg/dl, 6.3-23 mg/dl, and 1.9-9.1 CH50 units, respectively. Storage at -20 C resulted in a 50% reduction in values. Hence, storage at -70 C is recommended. As the level of pericardial-fluid total hemolytic complement is normally low, caution is needed in interpreting its apparent reduction in various immunologic diseases.
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U2 - 10.1093/ajcp/72.6.972
DO - 10.1093/ajcp/72.6.972
M3 - Article
C2 - 517464
AN - SCOPUS:0018639924
SN - 0002-9173
VL - 72
SP - 972
EP - 974
JO - American journal of clinical pathology
JF - American journal of clinical pathology
IS - 6
ER -