Pharmacology of medications used for ovarian stimulation

Alexander M. Quaas; Richard S. Legro

doi:10.1016/j.beem.2018.10.002

Pharmacology of medications used for ovarian stimulation

Alexander M. Quaas, Richard S. Legro

Research output: Contribution to journal › Review article › peer-review

31 Scopus citations

Abstract

Medications to stimulate the ovaries may be used to induce ovulation in patients with anovulatory infertility or to hyperstimulate the ovaries in a controlled fashion in ovulatory patients as part of assisted reproductive treatments (ART). The pharmacology of all current major medications used to stimulate ovarian function is reviewed in this article, including letrozole, clomiphene citrate, gonadotropins, and pulsatile gonadotropin releasing hormone (GnRH). Novel potential compounds and adjuvant treatment approaches are also discussed, such as kisspeptin agonists and androgens.

Original language	English (US)
Pages (from-to)	21-33
Number of pages	13
Journal	Best Practice and Research: Clinical Endocrinology and Metabolism
Volume	33
Issue number	1
DOIs	https://doi.org/10.1016/j.beem.2018.10.002
State	Published - Feb 2019

All Science Journal Classification (ASJC) codes

Endocrinology, Diabetes and Metabolism
Endocrinology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.beem.2018.10.002

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abstract = "Medications to stimulate the ovaries may be used to induce ovulation in patients with anovulatory infertility or to hyperstimulate the ovaries in a controlled fashion in ovulatory patients as part of assisted reproductive treatments (ART). The pharmacology of all current major medications used to stimulate ovarian function is reviewed in this article, including letrozole, clomiphene citrate, gonadotropins, and pulsatile gonadotropin releasing hormone (GnRH). Novel potential compounds and adjuvant treatment approaches are also discussed, such as kisspeptin agonists and androgens.",

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AU - Legro, Richard S.

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AB - Medications to stimulate the ovaries may be used to induce ovulation in patients with anovulatory infertility or to hyperstimulate the ovaries in a controlled fashion in ovulatory patients as part of assisted reproductive treatments (ART). The pharmacology of all current major medications used to stimulate ovarian function is reviewed in this article, including letrozole, clomiphene citrate, gonadotropins, and pulsatile gonadotropin releasing hormone (GnRH). Novel potential compounds and adjuvant treatment approaches are also discussed, such as kisspeptin agonists and androgens.

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Pharmacology of medications used for ovarian stimulation

Abstract

All Science Journal Classification (ASJC) codes

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