TY - JOUR
T1 - Phenytoin decreases the blood concentrations of sirolimus in a liver transplant recipient
T2 - A case report
AU - Fridell, Jonathan A.
AU - Jain, Ashok Kumar B.
AU - Patel, Kusum
AU - Virji, Mohamed
AU - Rao, K. N.
AU - Fung, John J.
AU - Venkataramanan, Raman
PY - 2003/2
Y1 - 2003/2
N2 - This report documents that coadministration of phenytoin leads to decreased blood concentrations and area under the blood concentration-time curve of sirolimus in a liver transplant patient. It is essential to monitor the blood concentrations of sirolimus and adjust the sirolimus dosage when phenytoin administration begins or ends.
AB - This report documents that coadministration of phenytoin leads to decreased blood concentrations and area under the blood concentration-time curve of sirolimus in a liver transplant patient. It is essential to monitor the blood concentrations of sirolimus and adjust the sirolimus dosage when phenytoin administration begins or ends.
UR - https://www.scopus.com/pages/publications/0037304694
UR - https://www.scopus.com/pages/publications/0037304694#tab=citedBy
U2 - 10.1097/00007691-200302000-00019
DO - 10.1097/00007691-200302000-00019
M3 - Article
C2 - 12548156
AN - SCOPUS:0037304694
SN - 0163-4356
VL - 25
SP - 117
EP - 119
JO - Therapeutic Drug Monitoring
JF - Therapeutic Drug Monitoring
IS - 1
ER -