Abstract
Using a panel of human/rodent somatic cell hybrids and human lymphoblast lines segregating 18 different human X-chromosome rearrangements and deletions, we have assigned 60 DNA markers to the physical map of the X chromosome from Xp21.1 to Xq21.3. Data from Southern blot hybridization and polymerase chain reaction (PCR) amplification assign these markers to 15 primary map intervals. This provides a basis for further long-range cloning and mapping of the pericentromeric region of the X chromosome.
Original language | English (US) |
---|---|
Pages (from-to) | 352-363 |
Number of pages | 12 |
Journal | Genomics |
Volume | 11 |
Issue number | 2 |
DOIs | |
State | Published - Oct 1991 |
All Science Journal Classification (ASJC) codes
- Genetics