TY - JOUR
T1 - Placental-site trophoblastic tumor with PET scan-detected surgically treated lung metastasis
AU - Nieves, Lucybeth
AU - Hoffman, James
AU - Allen, Gretchen
AU - Currie, John
AU - Sorosky, Joel I.
PY - 2008/6
Y1 - 2008/6
N2 - Metastatic placental-site trophoblastic tumor (PSTT) continues to be a diagnostic and management dilemma due to its relative resistance to chemotherapy and the difficulties in diagnosing such a rare tumor. We describe a 35-year-old woman with PSTT presenting with irregular bleeding and a mass in the lung. Dilation and curettage provided the diagnosis of PSTT by frozen section of the specimen. Subsequently, a total abdominal hysterectomy was performed and the patient received three cycles of EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) Positron emission tomography (PET) scan confirmed a persistent lung nodule that was treated with wedge resection. She is currently in clinical remission. Surgery may have a role in salvaging a patient with persistent PET-positive disease after chemotherapy.
AB - Metastatic placental-site trophoblastic tumor (PSTT) continues to be a diagnostic and management dilemma due to its relative resistance to chemotherapy and the difficulties in diagnosing such a rare tumor. We describe a 35-year-old woman with PSTT presenting with irregular bleeding and a mass in the lung. Dilation and curettage provided the diagnosis of PSTT by frozen section of the specimen. Subsequently, a total abdominal hysterectomy was performed and the patient received three cycles of EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) Positron emission tomography (PET) scan confirmed a persistent lung nodule that was treated with wedge resection. She is currently in clinical remission. Surgery may have a role in salvaging a patient with persistent PET-positive disease after chemotherapy.
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U2 - 10.1007/s10147-007-0721-7
DO - 10.1007/s10147-007-0721-7
M3 - Article
C2 - 18553238
AN - SCOPUS:45749152586
SN - 1341-9625
VL - 13
SP - 263
EP - 265
JO - International Journal of Clinical Oncology
JF - International Journal of Clinical Oncology
IS - 3
ER -