Placental-site trophoblastic tumor with PET scan-detected surgically treated lung metastasis

Lucybeth Nieves; James Hoffman; Gretchen Allen; John Currie; Joel I. Sorosky

doi:10.1007/s10147-007-0721-7

Placental-site trophoblastic tumor with PET scan-detected surgically treated lung metastasis

Lucybeth Nieves
, James Hoffman
, Gretchen Allen
, John Currie
, Joel I. Sorosky

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Metastatic placental-site trophoblastic tumor (PSTT) continues to be a diagnostic and management dilemma due to its relative resistance to chemotherapy and the difficulties in diagnosing such a rare tumor. We describe a 35-year-old woman with PSTT presenting with irregular bleeding and a mass in the lung. Dilation and curettage provided the diagnosis of PSTT by frozen section of the specimen. Subsequently, a total abdominal hysterectomy was performed and the patient received three cycles of EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) Positron emission tomography (PET) scan confirmed a persistent lung nodule that was treated with wedge resection. She is currently in clinical remission. Surgery may have a role in salvaging a patient with persistent PET-positive disease after chemotherapy.

Original language	English (US)
Pages (from-to)	263-265
Number of pages	3
Journal	International Journal of Clinical Oncology
Volume	13
Issue number	3
DOIs	https://doi.org/10.1007/s10147-007-0721-7
State	Published - Jun 2008

All Science Journal Classification (ASJC) codes

Surgery
Hematology
Oncology

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title = "Placental-site trophoblastic tumor with PET scan-detected surgically treated lung metastasis",

abstract = "Metastatic placental-site trophoblastic tumor (PSTT) continues to be a diagnostic and management dilemma due to its relative resistance to chemotherapy and the difficulties in diagnosing such a rare tumor. We describe a 35-year-old woman with PSTT presenting with irregular bleeding and a mass in the lung. Dilation and curettage provided the diagnosis of PSTT by frozen section of the specimen. Subsequently, a total abdominal hysterectomy was performed and the patient received three cycles of EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) Positron emission tomography (PET) scan confirmed a persistent lung nodule that was treated with wedge resection. She is currently in clinical remission. Surgery may have a role in salvaging a patient with persistent PET-positive disease after chemotherapy.",

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T1 - Placental-site trophoblastic tumor with PET scan-detected surgically treated lung metastasis

AU - Nieves, Lucybeth

AU - Hoffman, James

AU - Allen, Gretchen

AU - Currie, John

AU - Sorosky, Joel I.

PY - 2008/6

Y1 - 2008/6

N2 - Metastatic placental-site trophoblastic tumor (PSTT) continues to be a diagnostic and management dilemma due to its relative resistance to chemotherapy and the difficulties in diagnosing such a rare tumor. We describe a 35-year-old woman with PSTT presenting with irregular bleeding and a mass in the lung. Dilation and curettage provided the diagnosis of PSTT by frozen section of the specimen. Subsequently, a total abdominal hysterectomy was performed and the patient received three cycles of EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) Positron emission tomography (PET) scan confirmed a persistent lung nodule that was treated with wedge resection. She is currently in clinical remission. Surgery may have a role in salvaging a patient with persistent PET-positive disease after chemotherapy.

AB - Metastatic placental-site trophoblastic tumor (PSTT) continues to be a diagnostic and management dilemma due to its relative resistance to chemotherapy and the difficulties in diagnosing such a rare tumor. We describe a 35-year-old woman with PSTT presenting with irregular bleeding and a mass in the lung. Dilation and curettage provided the diagnosis of PSTT by frozen section of the specimen. Subsequently, a total abdominal hysterectomy was performed and the patient received three cycles of EMA-CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine) Positron emission tomography (PET) scan confirmed a persistent lung nodule that was treated with wedge resection. She is currently in clinical remission. Surgery may have a role in salvaging a patient with persistent PET-positive disease after chemotherapy.

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Placental-site trophoblastic tumor with PET scan-detected surgically treated lung metastasis

Abstract

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