TY - JOUR
T1 - Plasma exchange in the intensive care unit
T2 - a narrative review
AU - the Nine-i Investigators
AU - Bauer, Philippe R.
AU - Ostermann, Marlies
AU - Russell, Lene
AU - Robba, Chiara
AU - David, Sascha
AU - Ferreyro, Bruno L.
AU - Cid, Joan
AU - Castro, Pedro
AU - Juffermans, Nicole P.
AU - Montini, Luca
AU - Pirani, Tasneem
AU - Van De Louw, Andry
AU - Nielsen, Nathan
AU - Wendon, Julia
AU - Brignier, Anne C.
AU - Schetz, Miet
AU - Kielstein, Jan T.
AU - Winters, Jeffrey L.
AU - Azoulay, Elie
AU - Buchtele, Nina
AU - Staudinger, Thomas
AU - Heinz, Gottfried
AU - Sengölge, Gürkan
AU - Zauner, Christian
AU - Jaksch, Peter
AU - Amrein, Karin
AU - Schellongowski, Peter
AU - Staudinger, Thomas
AU - Meert, Anne Pascale
AU - Benoit, Dominique
AU - Taccone, Fabio Silvio
AU - de Moraes, Ana Paula Pierre
AU - Viana, William
AU - Moralez, Guilliana
AU - Lishoa, Thiago
AU - Soares, Marcio
AU - Salluh, Jorge
AU - Silva, U. V.
AU - Shah, Sumech
AU - Mehta, Sangeeta
AU - Munshi, Laveena
AU - Martin, Balik
AU - Thomas, Karvunidis
AU - Rusinova, Katerina
AU - Nelsen, Jonas
AU - Moeller, Ann M.
AU - Perner, Anders
AU - Meyhoff, Sylvest
AU - Bukan, Ramin Brandt
AU - Nielsen, Lene B.
N1 - Publisher Copyright:
© 2022, Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2022/10
Y1 - 2022/10
N2 - In this narrative review, we discuss the relevant issues of therapeutic plasma exchange (TPE) in critically ill patients. For many conditions, the optimal indication, device type, frequency, duration, type of replacement fluid and criteria for stopping TPE are uncertain. TPE is a potentially lifesaving but also invasive procedure with risk of adverse events and complications and requires close monitoring by experienced teams. In the intensive care unit (ICU), the indications for TPE can be divided into (1) absolute, well-established, and evidence-based, for which TPE is recognized as first-line therapy, (2) relative, for which TPE is a recognized second-line treatment (alone or combined) and (3) rescue therapy, where TPE is used with a limited or theoretical evidence base. New indications are emerging and ongoing knowledge gaps, notably regarding the use of TPE during critical illness, support the establishment of a TPE registry dedicated to intensive care medicine.
AB - In this narrative review, we discuss the relevant issues of therapeutic plasma exchange (TPE) in critically ill patients. For many conditions, the optimal indication, device type, frequency, duration, type of replacement fluid and criteria for stopping TPE are uncertain. TPE is a potentially lifesaving but also invasive procedure with risk of adverse events and complications and requires close monitoring by experienced teams. In the intensive care unit (ICU), the indications for TPE can be divided into (1) absolute, well-established, and evidence-based, for which TPE is recognized as first-line therapy, (2) relative, for which TPE is a recognized second-line treatment (alone or combined) and (3) rescue therapy, where TPE is used with a limited or theoretical evidence base. New indications are emerging and ongoing knowledge gaps, notably regarding the use of TPE during critical illness, support the establishment of a TPE registry dedicated to intensive care medicine.
UR - http://www.scopus.com/inward/record.url?scp=85136066400&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85136066400&partnerID=8YFLogxK
U2 - 10.1007/s00134-022-06793-z
DO - 10.1007/s00134-022-06793-z
M3 - Review article
C2 - 35960275
AN - SCOPUS:85136066400
SN - 0342-4642
VL - 48
SP - 1382
EP - 1396
JO - Intensive Care Medicine
JF - Intensive Care Medicine
IS - 10
ER -