TY - GEN
T1 - Plasma lithography for probing collective cell behaviors
AU - Junkin, Michael
AU - Wong, Pak Kin
PY - 2011
Y1 - 2011
N2 - Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography is demonstrated to facilitate quantification of collective cell migratory behaviors including the overall speed and the probability of velocity change upon cell-cell contact. This quantitative information in cell-cell interactions will allow us to understand the dynamics of collective cell migration from a systems biology perspective.
AB - Collective cell motions play essential roles in the regulation of various complex biological processes such as embryogenesis, tissue regeneration, and carcinogenesis. In this study, we present a novel plasma lithography technique for creating surface functionalized confinements toward the investigation of collective cell migration. The ability to confine cells one-dimensionally using plasma lithography is demonstrated to facilitate quantification of collective cell migratory behaviors including the overall speed and the probability of velocity change upon cell-cell contact. This quantitative information in cell-cell interactions will allow us to understand the dynamics of collective cell migration from a systems biology perspective.
UR - http://www.scopus.com/inward/record.url?scp=80053309614&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053309614&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2011.6017306
DO - 10.1109/NEMS.2011.6017306
M3 - Conference contribution
AN - SCOPUS:80053309614
SN - 9781612847757
T3 - NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
SP - 105
EP - 108
BT - NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
T2 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
Y2 - 20 February 2011 through 23 February 2011
ER -