TY - JOUR
T1 - Polydimethylsiloxane-based polyurethanes
T2 - Phase-separated morphology and in vitro oxidative biostability
AU - Choi, Taeyi
AU - Weksler, Jadwiga
AU - Padsalgikar, Ajay
AU - Hernndez, Rebeca
AU - Runt, James
N1 - Funding Information:
ADepartment of Materials Science and Engineering, The Pennsylvania State University, University Park, PA 16802, USA. BAorTech Biomaterials, Dalmore Drive, Caribbean Park, Scoresby, Vic. 3179, Australia. CInstituto de Ciencia y Tecnología de Polímeros, Consejo Superior de Investigaciones Cientificas, Juan de la Cierva, 328006 Madrid, Spain. DCorresponding author. Email: runt@matse.psu.edu
PY - 2009
Y1 - 2009
N2 - Three series of segmented polyurethane block copolymers were synthesized using 4,4′-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BDO) or 1,3-bis(4-hydroxybutyl)tetramethyl disiloxane (BHTD) as the hard segments, and soft segments composed of poly(dimethyl siloxane) (PDMS)-based and poly(hexamethylene oxide) (PHMO) macrodiols. Copolymers synthesized with the PDMS macrodiol and PDMS and PHMO macrodiol mixtures consist of three microphases: a PDMS phase, hard domains, and a mixed phase of PHMO (when present), PDMS ether end-group segments and some dissolved hard segments. Degrees of phase separation were characterized using small-angle X-ray scattering by applying a pseudo two-phase model, and the morphology resulting from unlike segment demixing was found to be closely related to the in vitro oxidative biostability of these segmented polyurethanes.
AB - Three series of segmented polyurethane block copolymers were synthesized using 4,4′-methylenediphenyl diisocyanate (MDI) and 1,4-butanediol (BDO) or 1,3-bis(4-hydroxybutyl)tetramethyl disiloxane (BHTD) as the hard segments, and soft segments composed of poly(dimethyl siloxane) (PDMS)-based and poly(hexamethylene oxide) (PHMO) macrodiols. Copolymers synthesized with the PDMS macrodiol and PDMS and PHMO macrodiol mixtures consist of three microphases: a PDMS phase, hard domains, and a mixed phase of PHMO (when present), PDMS ether end-group segments and some dissolved hard segments. Degrees of phase separation were characterized using small-angle X-ray scattering by applying a pseudo two-phase model, and the morphology resulting from unlike segment demixing was found to be closely related to the in vitro oxidative biostability of these segmented polyurethanes.
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U2 - 10.1071/CH09096
DO - 10.1071/CH09096
M3 - Article
AN - SCOPUS:69049098390
SN - 0004-9425
VL - 62
SP - 794
EP - 798
JO - Australian Journal of Chemistry
JF - Australian Journal of Chemistry
IS - 8
ER -