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Polyploidy as an Adaptation against Loss of Heterozygosity in Cancer
Marco Archetti
Biology
Huck Institutes of the Life Sciences
Penn State Cancer Institute
Cancer Institute, Next-Generation Therapies
Research output
:
Contribution to journal
›
Article
›
peer-review
8
Scopus citations
Overview
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Keyphrases
In Cancer
100%
Adaptation
100%
Loss of Heterozygosity
100%
Polyploidy
100%
Cancer Cells
50%
Diploid Cell
50%
Tumor
25%
Tumor Progression
25%
Mitosis
25%
Recombination
25%
Cell Fusion
25%
Non-adaptive
25%
Genomic Instability
25%
Computational Prediction
25%
Deleterious Effects
25%
Heterozygosity
25%
Tumor Resistance
25%
Asexual Reproduction
25%
Mutant Cells
25%
Selective Advantage
25%
Loss Reduction
25%
Ploidy
25%
Deleterious mutations
25%
Mitotic Recombination
25%
Resistance to Therapy
25%
Adaptogen
25%
Mitotic Cells
25%
Endomitosis
25%
Biochemistry, Genetics and Molecular Biology
Polyploid
100%
Loss of Heterozygosity
100%
Diploidy
40%
Cancer Cell
40%
Cell Fusion
20%
Heterozygosity
20%
Genome Instability
20%
Tumor Progression
20%
Mitotic Recombination
20%
Cell Mutant
20%
Ploidy
20%