Post–Covid-19 Cholangiopathy—A New Indication for Liver Transplantation: A Case Report

Francisco A. Durazo, Allyssa A. Nicholas, Jennifer J. Mahaffey, Shannon Sova, John J. Evans, Juan Pablo Trivella, Veronica Loy, Joohyun Kim, Michael A. Zimmerman, Johnny C. Hong

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Liver injury is one of the nonpulmonary manifestations described in coronavirus disease 2019 (COVID-19). Post–COVID-19 cholangiopathy is a special entity of liver injury that has been suggested as a variant of secondary sclerosing cholangitis in critically ill patients (SSC-CIP). In the general population, the outcome of SSC-CIP has been reported to be poor without orthotopic liver transplantation (OLT). However, the role of OLT for post–COVID-19 cholangiopathy is unknown. We present a case report of a 47-year-old man who recovered from acute respiratory distress syndrome from COVID-19 and subsequently developed end-stage liver disease from post–COVID-19 cholangiopathy. The patient underwent OLT and is doing well with normal liver tests for 7 months. To our knowledge, this is the first case report of a patient who underwent successful liver transplantation for post–COVID-19 cholangiopathy.

Original languageEnglish (US)
Pages (from-to)1132-1137
Number of pages6
JournalTransplantation proceedings
Issue number4
StatePublished - May 2021

All Science Journal Classification (ASJC) codes

  • Surgery
  • Transplantation


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