TY - JOUR
T1 - Posterior reversible encephalopathy syndrome in pediatric patients
T2 - pathophysiology, diagnosis, and management
AU - Ghali, Michael G.Z.
AU - Davanzo, Justin
AU - Leo, Madeline
AU - Rizk, Elias
N1 - Publisher Copyright:
© 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2019/8/24
Y1 - 2019/8/24
N2 - Posterior reversible encephalopathy syndrome (PRES) is well-described in adults, but has been reported with relative rarity in children, usually occurring in the context of chemotherapy for acute leukemia. Pathogenesis involves perturbed cerebral autoregulation leading to vasogenic edema predominantly affecting the parieto-occipital white matter, though involvement of the frontal and temporal lobes, as well as posterior fossa, is also described. We review the literature on the pathophysiology, diagnosis, and management of PRES in pediatric patients.
AB - Posterior reversible encephalopathy syndrome (PRES) is well-described in adults, but has been reported with relative rarity in children, usually occurring in the context of chemotherapy for acute leukemia. Pathogenesis involves perturbed cerebral autoregulation leading to vasogenic edema predominantly affecting the parieto-occipital white matter, though involvement of the frontal and temporal lobes, as well as posterior fossa, is also described. We review the literature on the pathophysiology, diagnosis, and management of PRES in pediatric patients.
UR - http://www.scopus.com/inward/record.url?scp=85073184301&partnerID=8YFLogxK
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U2 - 10.1080/10428194.2019.1594210
DO - 10.1080/10428194.2019.1594210
M3 - Review article
C2 - 31556774
AN - SCOPUS:85073184301
SN - 1042-8194
VL - 60
SP - 2365
EP - 2372
JO - Leukemia and Lymphoma
JF - Leukemia and Lymphoma
IS - 10
ER -
