Practical synthesis of chiral 9,9′-spirobixanthene-1,1′-diol

Weicheng Zhang, Shulin Wu, Zhaoguo Zhang, Hemant Yennawar, Xumu Zhang

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


A concise four-step synthesis of 9,9′-spirobixanthene-1,1′-diol is reported, featuring a practical preparation at large scale without the use of column chromatography purification. Co-crystallization with N-benzylcinchonidinium chloride and N-benzylquininium chloride rendered the optically pure product in both enantiomers.

Original languageEnglish (US)
Pages (from-to)4474-4477
Number of pages4
JournalOrganic and Biomolecular Chemistry
Issue number24
StatePublished - 2006

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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