@inproceedings{17ad12dd40584fcebf5a84d451f9b88e,
title = "Preclinical safety and effectiveness of a longer beam and burst duration for ultrasonic repositioning of urinary stones",
abstract = "In the first-in-human trial of ultrasonic propulsion, subjects passed collections of residual stone fragments after repositioning with a C5-2 probe. Here, effectiveness and safety in moving multiple fragments is compared between the C5-2 and a custom SC-50 probe that produces a longer beam and burst duration.",
author = "Barbrina Dunmire and Janssen, {Karmon M.} and Brand, {Timothy C.} and Cunitz, {Bryan W.} and Wang, {Yak Nam} and Simon, {Julianna C.} and Frank Starr and {Denny Liggitt}, H. and Jeff Thiel and Harper, {Jonathan D.} and Sorensen, {Mathew D.} and Bailey, {Michael R.}",
note = "Funding Information: Although successful in the clinical trial, the shorter focal beam and 50-ms bursts of the C5-2 probe did not expel any stones from the phantom's 30-mm deep calyx. The longer bursts of the SC-50 probe expelled all stones at both 4.5-cm and 9.5-cm {"}skin-to-stone{"} depths with lower probe heating compared to the C5-2. No treatment-related kidney injury was observed for burst durations of 10 minutes. A longer beam and burst duration improved expulsion of a stone and multiple stone fragments from a phantom over a broad range of clinically relevant penetration depths and did not cause kidney injury in animal studies. Work support by NIH NIDDK grant DK043881 and the National Space Biomedical Research Institute through NASA NCC 9-58. Publisher Copyright: {\textcopyright} 2017 IEEE.; 2017 IEEE International Ultrasonics Symposium, IUS 2017 ; Conference date: 06-09-2017 Through 09-09-2017",
year = "2017",
month = oct,
day = "31",
doi = "10.1109/ULTSYM.2017.8092038",
language = "English (US)",
series = "IEEE International Ultrasonics Symposium, IUS",
publisher = "IEEE Computer Society",
booktitle = "2017 IEEE International Ultrasonics Symposium, IUS 2017",
address = "United States",
}