Predictive value of recurrent DNA copy number variations

Abdullah K. Alqallaf; Ahmed H. Tewfik; Scott Brian Selleck; Rebecca L. Johnson

doi:10.1109/GENSIPS.2008.4555678

Predictive value of recurrent DNA copy number variations

Abdullah K. Alqallaf, Ahmed H. Tewfik, Scott Brian Selleck, Rebecca L. Johnson

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Recurrent copy number variations across multiple samples are increasingly used to identify the genes and the genomic locations that are statistically and biologically significant and correlated with certain diseases. In this paper, we evaluate the predictive power of copy number variations for detecting autism. We consider both recurrent copy number variations at one location and correlated recurrent copy number variations at multiple locations. In each case, we compare the ability of k-means and Fuzzy c-means algorithms to correctly classify autistic samples. Finally, we apply our proposed techniques on 51 samples of 25 apparently healthy and 26 autistic children.

Original language	English (US)
Title of host publication	GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics
DOIs	https://doi.org/10.1109/GENSIPS.2008.4555678
State	Published - 2008
Event	6th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'08 - Phoenix, AZ, United States Duration: Jun 8 2008 → Jun 10 2008

Publication series

Name	GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics

Other

Other	6th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'08
Country/Territory	United States
City	Phoenix, AZ
Period	6/8/08 → 6/10/08

All Science Journal Classification (ASJC) codes

Genetics
Signal Processing
Electrical and Electronic Engineering
Statistics, Probability and Uncertainty

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10.1109/GENSIPS.2008.4555678

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Alqallaf, A. K., Tewfik, A. H., Selleck, S. B., & Johnson, R. L. (2008). Predictive value of recurrent DNA copy number variations. In GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics Article 4555678 (GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics). https://doi.org/10.1109/GENSIPS.2008.4555678

@inproceedings{abc447bfc89f420ba772f76f41eab2b3,

title = "Predictive value of recurrent DNA copy number variations",

abstract = "Recurrent copy number variations across multiple samples are increasingly used to identify the genes and the genomic locations that are statistically and biologically significant and correlated with certain diseases. In this paper, we evaluate the predictive power of copy number variations for detecting autism. We consider both recurrent copy number variations at one location and correlated recurrent copy number variations at multiple locations. In each case, we compare the ability of k-means and Fuzzy c-means algorithms to correctly classify autistic samples. Finally, we apply our proposed techniques on 51 samples of 25 apparently healthy and 26 autistic children.",

author = "Alqallaf, {Abdullah K.} and Tewfik, {Ahmed H.} and Selleck, {Scott Brian} and Johnson, {Rebecca L.}",

year = "2008",

doi = "10.1109/GENSIPS.2008.4555678",

language = "English (US)",

isbn = "9781424423729",

series = "GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics",

booktitle = "GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics",

note = "6th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'08 ; Conference date: 08-06-2008 Through 10-06-2008",

}

Alqallaf, AK, Tewfik, AH, Selleck, SB & Johnson, RL 2008, Predictive value of recurrent DNA copy number variations. in GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics., 4555678, GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics, 6th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'08, Phoenix, AZ, United States, 6/8/08. https://doi.org/10.1109/GENSIPS.2008.4555678

Predictive value of recurrent DNA copy number variations. / Alqallaf, Abdullah K.; Tewfik, Ahmed H.; Selleck, Scott Brian et al.
GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics. 2008. 4555678 (GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Predictive value of recurrent DNA copy number variations

AU - Alqallaf, Abdullah K.

AU - Tewfik, Ahmed H.

AU - Selleck, Scott Brian

AU - Johnson, Rebecca L.

PY - 2008

Y1 - 2008

N2 - Recurrent copy number variations across multiple samples are increasingly used to identify the genes and the genomic locations that are statistically and biologically significant and correlated with certain diseases. In this paper, we evaluate the predictive power of copy number variations for detecting autism. We consider both recurrent copy number variations at one location and correlated recurrent copy number variations at multiple locations. In each case, we compare the ability of k-means and Fuzzy c-means algorithms to correctly classify autistic samples. Finally, we apply our proposed techniques on 51 samples of 25 apparently healthy and 26 autistic children.

AB - Recurrent copy number variations across multiple samples are increasingly used to identify the genes and the genomic locations that are statistically and biologically significant and correlated with certain diseases. In this paper, we evaluate the predictive power of copy number variations for detecting autism. We consider both recurrent copy number variations at one location and correlated recurrent copy number variations at multiple locations. In each case, we compare the ability of k-means and Fuzzy c-means algorithms to correctly classify autistic samples. Finally, we apply our proposed techniques on 51 samples of 25 apparently healthy and 26 autistic children.

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U2 - 10.1109/GENSIPS.2008.4555678

DO - 10.1109/GENSIPS.2008.4555678

M3 - Conference contribution

AN - SCOPUS:51549094035

SN - 9781424423729

T3 - GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics

BT - GENSIPS'08 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics

T2 - 6th IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS'08

Y2 - 8 June 2008 through 10 June 2008

ER -

Predictive value of recurrent DNA copy number variations

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All Science Journal Classification (ASJC) codes

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