TY - JOUR
T1 - Preparation of nitrophenylethylsilylated silica gel and its chromatographic properties, in the separation of polychrlorinated dibenzo-p-dioxins
AU - Kimata, Kazuhiro
AU - Hosoya, Ken
AU - Tanaka, Nobuo
AU - Araki, Takeo
AU - Patterson, D. G.
N1 - Funding Information:
This work was supported in part by the Mon-busho International Joint Research Program (No. 03044089), funded by the Ministry of Education. We are grateful to Drs. E. R. Barnhart and L. R. Alexander of the Centers for Disease Control, US Public Health Service, Professor K. Fukunishi of Kyoto Institute of Technology, Professor S. Terabe of Himeji Institute of Technology and Professor H. Miyata of Setsunan University for helpful suggestions.
PY - 1992/3/20
Y1 - 1992/3/20
N2 - Nitrophenylethylsilylated (NPE) silical gel was prepared from phenylethylsilylated silica gel by direct nitration, and its chromatographic properties were compared with those of C18 and pryrenylethyl (PYE) bonded phase in reversed-phase high-performance liquid chromatography. The NPE phase showed preferential retention for aromatic compounds, especially for those with dipolar character. In contrast, PYE phase showed preferential retention for symmetrically substituted aromatic compounds. The combination of NPE and PYE phases provided the selectivity required for the separation of isomers of polychlorinated aromatic compounds, namely polychlorobenzo-p-dioxins (PCDDs). The two stationary phases, having aromatic functionalities of opposite nature, also provided the possibility of structural assignment of PCDD isomers based on the chromatographic retention on the two phases.
AB - Nitrophenylethylsilylated (NPE) silical gel was prepared from phenylethylsilylated silica gel by direct nitration, and its chromatographic properties were compared with those of C18 and pryrenylethyl (PYE) bonded phase in reversed-phase high-performance liquid chromatography. The NPE phase showed preferential retention for aromatic compounds, especially for those with dipolar character. In contrast, PYE phase showed preferential retention for symmetrically substituted aromatic compounds. The combination of NPE and PYE phases provided the selectivity required for the separation of isomers of polychlorinated aromatic compounds, namely polychlorobenzo-p-dioxins (PCDDs). The two stationary phases, having aromatic functionalities of opposite nature, also provided the possibility of structural assignment of PCDD isomers based on the chromatographic retention on the two phases.
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U2 - 10.1016/0021-9673(92)85148-M
DO - 10.1016/0021-9673(92)85148-M
M3 - Article
AN - SCOPUS:0026552446
SN - 0021-9673
VL - 595
SP - 77
EP - 88
JO - Journal of Chromatography A
JF - Journal of Chromatography A
IS - 1-2
ER -