Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice

Keyphrases

• Cell Surface 100%
• Pro-apoptotic 100%
• Cyclic Peptide 100%
• Anticancer Therapeutics 100%
• Glucose-regulated Protein 78 (GRP78) 100%
• Tumor 16%
• Adhesion 16%
• Protein Domain 16%
• Apoptosis 16%
• Human Umbilical Vein Endothelial Cells (HUVECs) 16%
• Targeted Cells 16%
• Cancer Prognosis 16%
• In Cancer 8%
• Tumor Growth 8%
• Further Development 8%
• High Affinity 8%
• Overexpression 8%
• Endothelial Cells 8%
• Amino Acid Residues 8%
• Angiogenesis 8%
• Cancer Cells 8%
• P53 Pathway 8%
• Drug Target 8%
• Blood Vessels 8%
• Cancer Therapy 8%
• Intravenous Administration 8%
• Amides 8%
• Anticancer Drugs 8%
• Anti-apoptotic Proteins 8%
• Cancer Types 8%
• Tumor Angiogenesis 8%
• Protein-ligand 8%
• Peptidomimetics 8%
• Caspase-8 8%
• Hydrogen-deuterium Exchange Mass Spectrometry 8%
• Xenograft Tumor Growth 8%

Biochemistry, Genetics and Molecular Biology

• Target Cell 100%
• Anticancer 100%
• Glucose-Regulated Protein 100%
• Angiogenesis 16%
• Tumor Progression 16%
• Programmed Cell Death 16%
• MUC4 16%
• Amino Acids 8%
• Adenosine Triphosphate 8%
• C-Terminus 8%
• Cancer Cell 8%
• Drug Targeting 8%
• P53 8%
• Protein Ligand 8%
• Positron Emission Tomography 8%
• Peptidomimetic 8%
• Caspase 8 8%
• Hydrogen/Deuterium Exchange Mass Spectrometry 8%