Probing when dCas9 tolerates DNA mismatches

Research output: Contribution to journalArticlepeer-review

Abstract

Sensing changes in ionic current as barcoded DNA translocates through solid-state nanopores allows the study of how nucleotide sequences alter the DNA-binding specificity of the catalytically inactive Cas9 ribonucleoprotein complex.

Original languageEnglish (US)
Pages (from-to)207-208
Number of pages2
JournalNature Biomedical Engineering
Volume8
Issue number3
DOIs
StatePublished - Mar 2024

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Computer Science Applications

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