Processivity of the Kinesin-2 KIF3A results from rear head gating and not front head gating

Keyphrases

• Adenosine 20%
• Bound States 40%
• Dynein 20%
• Exchange Kinetics 20%
• First Encounter 20%
• Flow State 20%
• Gating Mechanism 20%
• Homodimer 20%
• Hydrolysis 20%
• Imido 20%
• Interdomain Linker 20%
• KIF3A 100%
• Kinesin 40%
• Kinesin-2 100%
• Kinetic Experiments 20%
• Load-dependent 20%
• Low Affinity 20%
• Melanosome 20%
• Microtubules 40%
• Motility 20%
• Multi-motor 20%
• Neck Linker 20%
• Nucleotide Binding 40%
• Processive 20%
• Processivity 100%
• Single Molecule 20%
• State Exchange 20%
• Steady-state Kinetics 20%
• Stepping Rate 20%
• Stopped Flow 20%
• Strain-dependent 20%
• Triphosphate 20%

Biochemistry, Genetics and Molecular Biology

• Adenosine Diphosphate 33%
• Adenosine Triphosphate 16%
• Dynein 16%
• Enzymatic Hydrolysis 16%
• Intraflagellar Transport 16%
• KIF3A 100%
• Kinesin 100%
• Melanosome 16%
• Processivity 100%
• Steady State 16%