Production of solavetivone by immobilized cells of Hyoscyamus muticus

S. V. Ramakrishna; G. Ramakrishna Reddy; Wayne R. Curtis; Arthur E. Humphrey

doi:10.1007/BF00128323

Production of solavetivone by immobilized cells of Hyoscyamus muticus

S. V. Ramakrishna, G. Ramakrishna Reddy, Wayne R. Curtis, Arthur E. Humphrey

Chemical Engineering

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The secretion of solavetivone, a phytoalexin, by the cells of Hyoscyamus muticus in response to fungal elicitation has been enhanced by gel entrapment in calcium alginate. The immobilized cells produced 53% higher product and exhibited sustained biosynthetic activity in repeated batch cycles when compared with suspended cells. Providing a non-elicited media exchange and a sufficient interval of time between repeated infection (elicitation) gave greater productivity. Apparently the cells need a period to recover from the infection.

Original language	English (US)
Pages (from-to)	301-306
Number of pages	6
Journal	Biotechnology Letters
Volume	15
Issue number	3
DOIs	https://doi.org/10.1007/BF00128323
State	Published - Mar 1 1993

All Science Journal Classification (ASJC) codes

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1007/BF00128323

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title = "Production of solavetivone by immobilized cells of Hyoscyamus muticus",

abstract = "The secretion of solavetivone, a phytoalexin, by the cells of Hyoscyamus muticus in response to fungal elicitation has been enhanced by gel entrapment in calcium alginate. The immobilized cells produced 53% higher product and exhibited sustained biosynthetic activity in repeated batch cycles when compared with suspended cells. Providing a non-elicited media exchange and a sufficient interval of time between repeated infection (elicitation) gave greater productivity. Apparently the cells need a period to recover from the infection.",

author = "Ramakrishna, {S. V.} and Reddy, {G. Ramakrishna} and Curtis, {Wayne R.} and Humphrey, {Arthur E.}",

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AU - Ramakrishna, S. V.

AU - Reddy, G. Ramakrishna

AU - Curtis, Wayne R.

AU - Humphrey, Arthur E.

PY - 1993/3/1

Y1 - 1993/3/1

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AB - The secretion of solavetivone, a phytoalexin, by the cells of Hyoscyamus muticus in response to fungal elicitation has been enhanced by gel entrapment in calcium alginate. The immobilized cells produced 53% higher product and exhibited sustained biosynthetic activity in repeated batch cycles when compared with suspended cells. Providing a non-elicited media exchange and a sufficient interval of time between repeated infection (elicitation) gave greater productivity. Apparently the cells need a period to recover from the infection.

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JF - Biotechnology Letters

IS - 3

ER -

Production of solavetivone by immobilized cells of Hyoscyamus muticus

Abstract

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