Production of Specific Antisera to Human B Lymphocytes

Peter Goodfellow, Colin Barnstable, Elizabeth Jones, Walter F. Bodmer, Michael J. Crumpton, David Snary

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β2 microglobulin.

Original languageEnglish (US)
Pages (from-to)105-117
Number of pages13
JournalTissue Antigens
Issue number2
StatePublished - Feb 1976

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Biochemistry
  • Genetics


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