Production of Specific Antisera to Human B Lymphocytes

Peter Goodfellow; Colin Barnstable; Elizabeth Jones; Walter F. Bodmer; Michael J. Crumpton; David Snary

doi:10.1111/j.1399-0039.1976.tb01039.x

Production of Specific Antisera to Human B Lymphocytes

Peter Goodfellow
, Colin Barnstable
, Elizabeth Jones
, Walter F. Bodmer
, Michael J. Crumpton
, David Snary

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β₂ microglobulin.

Original language	English (US)
Pages (from-to)	105-117
Number of pages	13
Journal	Tissue Antigens
Volume	7
Issue number	2
DOIs	https://doi.org/10.1111/j.1399-0039.1976.tb01039.x
State	Published - Feb 1976

All Science Journal Classification (ASJC) codes

Immunology and Allergy
Immunology
Biochemistry
Genetics

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10.1111/j.1399-0039.1976.tb01039.x

Cite this

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title = "Production of Specific Antisera to Human B Lymphocytes",

abstract = "Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β2 microglobulin.",

author = "Peter Goodfellow and Colin Barnstable and Elizabeth Jones and Bodmer, \{Walter F.\} and Crumpton, \{Michael J.\} and David Snary",

year = "1976",

month = feb,

doi = "10.1111/j.1399-0039.1976.tb01039.x",

language = "English (US)",

volume = "7",

pages = "105--117",

journal = "Tissue Antigens",

issn = "0001-2815",

publisher = "Wiley-Blackwell Publishing Ltd",

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TY - JOUR

T1 - Production of Specific Antisera to Human B Lymphocytes

AU - Goodfellow, Peter

AU - Barnstable, Colin

AU - Jones, Elizabeth

AU - Bodmer, Walter F.

AU - Crumpton, Michael J.

AU - Snary, David

PY - 1976/2

Y1 - 1976/2

N2 - Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β2 microglobulin.

AB - Antisera have been prepared, in mice and rabbits, to membrane and sub‐membrane fractions of human B lymphocyte derived lymphoid lines. Antisera to a protein subfraction were, after only minimal absorption, specific for human peripheral B lymphocytes, monocytes and B cell derived lymphoid lines. The antigen(s) recognised by these antisera were not the same as the previously described B‐cell markers; immunoglobulin, Fc receptor, complement receptor and Ia antigens. The antigen(s) could not be removed from cells by lysostrip with anti‐ β2 microglobulin.

UR - https://www.scopus.com/pages/publications/0017259366

UR - https://www.scopus.com/pages/publications/0017259366#tab=citedBy

U2 - 10.1111/j.1399-0039.1976.tb01039.x

DO - 10.1111/j.1399-0039.1976.tb01039.x

M3 - Article

C2 - 775683

AN - SCOPUS:0017259366

SN - 0001-2815

VL - 7

SP - 105

EP - 117

JO - Tissue Antigens

JF - Tissue Antigens

IS - 2

ER -

Production of Specific Antisera to Human B Lymphocytes

Abstract

All Science Journal Classification (ASJC) codes

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