Prognostic markers and targeted therapies for renal cell carcinoma

S. Elena Gimenez, Ciprian Secasan, Jay D. Raman

Research output: Contribution to journalReview articlepeer-review


Management of advanced renal cell carcinoma remains a persistent clinical challenge with high morbidity and mortality for a large proportion of patients. Until recently, available medical immunotherapy regimens yielded a therapeutic response in only 20% of patients. Advances in the understanding of molecular mechanism, of renal cell carcinoma have led to a rapidly expanding body of work exploring biomarkers for the disease and targeted therapeutics. We review current investigations into biomarkers and novel therapies for renal cell carcinoma, discuss the concept of anticancer vaccines, and propose a novel target for anticancer vaccine-development.

Original languageEnglish (US)
Pages (from-to)197-205
Number of pages9
JournalFuture Oncology
Issue number2
StatePublished - 2009

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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