PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED

Anthony J. Politza; Tianyi Liu; Weihua Guan

PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED

Anthony J. Politza, Tianyi Liu, Weihua Guan

Electrical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

For numerous diseases across the globe, nucleic acid testing remains the clinical standard. However, there is a need for these methods to be field deployable. Recent improvements in optical detection and isothermal amplification have pushed POCT devices closer to laboratory standards. However, sample preparation remains a bottleneck that has not seen improvements. Here we present an automated device using paramagnetic beads for nucleic acid extraction in under 10 minutes. Linking our device with microfluidics creates a system that is fully automated, user-friendly, ultra-portable, notably accessible, and sample adaptable.

Original language	English (US)
Title of host publication	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022
Editors	Reza Ghodssi, Jenna F. Chan
Publisher	Transducer Research Foundation
Pages	150-153
Number of pages	4
ISBN (Electronic)	9781940470047
State	Published - 2022
Event	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022 - Hilton Head, United States Duration: Jun 5 2022 → Jun 9 2022

Publication series

Name	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

Conference

Conference	2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022
Country/Territory	United States
City	Hilton Head
Period	6/5/22 → 6/9/22

All Science Journal Classification (ASJC) codes

Hardware and Architecture
Electrical and Electronic Engineering

Cite this

Politza, A. J., Liu, T., & Guan, W. (2022). PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED. In R. Ghodssi, & J. F. Chan (Eds.), 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022 (pp. 150-153). (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022). Transducer Research Foundation.

Politza, Anthony J. ; Liu, Tianyi ; Guan, Weihua. / PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED. 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. editor / Reza Ghodssi ; Jenna F. Chan. Transducer Research Foundation, 2022. pp. 150-153 (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022).

@inproceedings{ec4e10d822544fa7a89362c02b286808,

title = "PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED",

abstract = "For numerous diseases across the globe, nucleic acid testing remains the clinical standard. However, there is a need for these methods to be field deployable. Recent improvements in optical detection and isothermal amplification have pushed POCT devices closer to laboratory standards. However, sample preparation remains a bottleneck that has not seen improvements. Here we present an automated device using paramagnetic beads for nucleic acid extraction in under 10 minutes. Linking our device with microfluidics creates a system that is fully automated, user-friendly, ultra-portable, notably accessible, and sample adaptable.",

author = "Politza, \{Anthony J.\} and Tianyi Liu and Weihua Guan",

note = "Publisher Copyright: {\textcopyright} 2022 TRF.; 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022 ; Conference date: 05-06-2022 Through 09-06-2022",

year = "2022",

language = "English (US)",

series = "2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022",

publisher = "Transducer Research Foundation",

pages = "150--153",

editor = "Reza Ghodssi and Chan, \{Jenna F.\}",

booktitle = "2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022",

}

Politza, AJ, Liu, T & Guan, W 2022, PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED. in R Ghodssi & JF Chan (eds), 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022, Transducer Research Foundation, pp. 150-153, 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022, Hilton Head, United States, 6/5/22.

PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED. / Politza, Anthony J.; Liu, Tianyi; Guan, Weihua.
2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. ed. / Reza Ghodssi; Jenna F. Chan. Transducer Research Foundation, 2022. p. 150-153 (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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T1 - PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED

AU - Politza, Anthony J.

AU - Liu, Tianyi

AU - Guan, Weihua

PY - 2022

Y1 - 2022

N2 - For numerous diseases across the globe, nucleic acid testing remains the clinical standard. However, there is a need for these methods to be field deployable. Recent improvements in optical detection and isothermal amplification have pushed POCT devices closer to laboratory standards. However, sample preparation remains a bottleneck that has not seen improvements. Here we present an automated device using paramagnetic beads for nucleic acid extraction in under 10 minutes. Linking our device with microfluidics creates a system that is fully automated, user-friendly, ultra-portable, notably accessible, and sample adaptable.

AB - For numerous diseases across the globe, nucleic acid testing remains the clinical standard. However, there is a need for these methods to be field deployable. Recent improvements in optical detection and isothermal amplification have pushed POCT devices closer to laboratory standards. However, sample preparation remains a bottleneck that has not seen improvements. Here we present an automated device using paramagnetic beads for nucleic acid extraction in under 10 minutes. Linking our device with microfluidics creates a system that is fully automated, user-friendly, ultra-portable, notably accessible, and sample adaptable.

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M3 - Conference contribution

AN - SCOPUS:85172701913

T3 - 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

SP - 150

EP - 153

BT - 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

A2 - Ghodssi, Reza

A2 - Chan, Jenna F.

PB - Transducer Research Foundation

T2 - 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022

Y2 - 5 June 2022 through 9 June 2022

ER -

Politza AJ, Liu T, Guan W. PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED. In Ghodssi R, Chan JF, editors, 2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022. Transducer Research Foundation. 2022. p. 150-153. (2022 Solid-State Sensors, Actuators and Microsystems Workshop, Hilton Head 2022).

PROGRAMMABLE MAGNETIC ROBOT (PROMAGBOT) FOR AUTOMATED NUCLEIC ACID EXTRACTION AT THE POINT OF NEED

Abstract

Publication series

Conference

All Science Journal Classification (ASJC) codes

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