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Programmable protein editing

Research output: Contribution to journalShort surveypeer-review

Abstract

Installation of unnatural chemical motifs and structures into proteins in living cells is challenging. Recent work by Beyer et al. demonstrated programmable protein editing by installing two split intein pairs into a protein of interest, which splice in a fully synthetic peptide sequence inside mammalian cells.

Original languageEnglish (US)
Pages (from-to)837-838
Number of pages2
JournalTrends in Biochemical Sciences
Volume50
Issue number10
DOIs
StatePublished - Oct 2025

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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