TY - JOUR
T1 - Project TENDR
T2 - Targeting environmental neuro-developmental risks. the TENDR consensus statement
AU - American College of Obstetricians and Gynecologists (ACOG)
AU - Child Neurology Society
AU - Endocrine Society
AU - International Neurotoxicology Association
AU - International Society for Children's Health and the Environment
AU - International Society for Environmental Epidemiology
AU - National Council of Asian Pacific Islander Physicians
AU - National Hispanic Medical Association
AU - National Medical Association
AU - Bennett, D.
AU - Bellinger, D. C.
AU - Birnbaum, L. S.
AU - Bradman, A.
AU - Chen, A.
AU - Cory-Slechta, D. A.
AU - Engel, S. M.
AU - Fallin, M. D.
AU - Halladay, A.
AU - Hauser, R.
AU - Hertz-Picciotto, I.
AU - Kwiatkowski, C. F.
AU - Lanphear, B. P.
AU - Marquez, E.
AU - Marty, M.
AU - McPartland, J.
AU - Newschaffer, C. J.
AU - Payne-Sturges, D.
AU - Patisaul, H. B.
AU - Perera, F. P.
AU - Ritz, B.
AU - Sass, J.
AU - Schantz, S. L.
AU - Webster, T. F.
AU - Whyatt, R. M.
AU - Woodruff, T. J.
AU - Zoeller, R. T.
AU - Anderko, L.
AU - Campbell, C.
AU - Conry, J. A.
AU - DeNicola, N.
AU - Gould, R. M.
AU - Hirtz, D.
AU - Huffling, K.
AU - Landrigan, P. J.
AU - Lavin, A.
AU - Miller, M.
AU - Mitchell, M. A.
AU - Rubin, L.
AU - Schettler, T.
AU - Tran, H. L.
AU - Acosta, A.
AU - Brody, C.
AU - Miller, E.
AU - Miller, P.
AU - Swanson, M.
AU - Witherspoon, N. O.
N1 - Publisher Copyright:
© 2016, Public Health Services, US Dept of Health and Human Services. All rights reserved.
PY - 2016/7
Y1 - 2016/7
N2 - Children in America today are at an unacceptably high risk of developing neurodevelopmental disorders that affect the brain and nervous system including autism, attention deficit hyperactivity disorder, intellectual disabilities, and other learning and behavioral disabilities. These are complex disorders with multiple causes—genetic, social, and environmental. The contribution of toxic chemicals to these disorders can be prevented. Approach: Leading scientific and medical experts, along with children’s health advocates, came together in 2015 under the auspices of Project TENDR: Targeting Environmental Neuro-Developmental Risks to issue a call to action to reduce widespread exposures to chemicals that interfere with fetal and children’s brain development. Based on the available scientific evidence, the TENDR authors have identified prime examples of toxic chemicals and pollutants that increase children’s risks for neurodevelopmental disorders. These include chemicals that are used extensively in consumer products and that have become widespread in the environment. Some are chemicals to which children and pregnant women are regularly exposed, and they are detected in the bodies of virtually all Americans in national surveys conducted by the U.S. Centers for Disease Control and Prevention. The vast majority of chemicals in industrial and consumer products undergo almost no testing for developmental neurotoxicity or other health effects. Conclusion: Based on these findings, we assert that the current system in the United States for evaluating scientific evidence and making health-based decisions about environmental chemicals is fundamentally broken. To help reduce the unacceptably high prevalence of neurodevelopmental disorders in our children, we must eliminate or significantly reduce exposures to chemicals that contribute to these conditions. We must adopt a new framework for assessing chemicals that have the potential to disrupt brain development and prevent the use of those that may pose a risk. This consensus statement lays the foundation for developing recommendations to monitor, assess, and reduce exposures to neurotoxic chemicals. These measures are urgently needed if we are to protect healthy brain development so that current and future generations can reach their fullest potential.
AB - Children in America today are at an unacceptably high risk of developing neurodevelopmental disorders that affect the brain and nervous system including autism, attention deficit hyperactivity disorder, intellectual disabilities, and other learning and behavioral disabilities. These are complex disorders with multiple causes—genetic, social, and environmental. The contribution of toxic chemicals to these disorders can be prevented. Approach: Leading scientific and medical experts, along with children’s health advocates, came together in 2015 under the auspices of Project TENDR: Targeting Environmental Neuro-Developmental Risks to issue a call to action to reduce widespread exposures to chemicals that interfere with fetal and children’s brain development. Based on the available scientific evidence, the TENDR authors have identified prime examples of toxic chemicals and pollutants that increase children’s risks for neurodevelopmental disorders. These include chemicals that are used extensively in consumer products and that have become widespread in the environment. Some are chemicals to which children and pregnant women are regularly exposed, and they are detected in the bodies of virtually all Americans in national surveys conducted by the U.S. Centers for Disease Control and Prevention. The vast majority of chemicals in industrial and consumer products undergo almost no testing for developmental neurotoxicity or other health effects. Conclusion: Based on these findings, we assert that the current system in the United States for evaluating scientific evidence and making health-based decisions about environmental chemicals is fundamentally broken. To help reduce the unacceptably high prevalence of neurodevelopmental disorders in our children, we must eliminate or significantly reduce exposures to chemicals that contribute to these conditions. We must adopt a new framework for assessing chemicals that have the potential to disrupt brain development and prevent the use of those that may pose a risk. This consensus statement lays the foundation for developing recommendations to monitor, assess, and reduce exposures to neurotoxic chemicals. These measures are urgently needed if we are to protect healthy brain development so that current and future generations can reach their fullest potential.
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U2 - 10.1289/EHP358
DO - 10.1289/EHP358
M3 - Article
C2 - 27479987
AN - SCOPUS:84977118072
SN - 0091-6765
VL - 124
SP - A118-A122
JO - Environmental health perspectives
JF - Environmental health perspectives
IS - 7
ER -