TY - JOUR
T1 - Prolonged retrograde amnesia following sedation with propofol in a 12-year-old boy
AU - Quraishi, Sadeq A.
AU - Girdharry, Tyrone D.
AU - Xu, Shu Guang
AU - Orkin, Fredrick K.
PY - 2007/4
Y1 - 2007/4
N2 - Propofol is commonly used for sedation in a variety of clinical settings, as well as for induction and maintenance of anesthesia. The ease with which propofol can be administered and titrated to clinical effect, in addition to its accepted safety profile, has made it the drug of choice for sedation in outpatient procedures, such as gastrointestinal endoscopy. While short-term amnesia is a well-known side-effect of propofol, we present the first documented case of prolonged retrograde amnesia following propofol administration in a pediatric patient. Possible mechanisms and clinical management strategies related to this unique event are discussed.
AB - Propofol is commonly used for sedation in a variety of clinical settings, as well as for induction and maintenance of anesthesia. The ease with which propofol can be administered and titrated to clinical effect, in addition to its accepted safety profile, has made it the drug of choice for sedation in outpatient procedures, such as gastrointestinal endoscopy. While short-term amnesia is a well-known side-effect of propofol, we present the first documented case of prolonged retrograde amnesia following propofol administration in a pediatric patient. Possible mechanisms and clinical management strategies related to this unique event are discussed.
UR - http://www.scopus.com/inward/record.url?scp=33847618211&partnerID=8YFLogxK
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U2 - 10.1111/j.1460-9592.2006.02123.x
DO - 10.1111/j.1460-9592.2006.02123.x
M3 - Article
C2 - 17359408
AN - SCOPUS:33847618211
SN - 1155-5645
VL - 17
SP - 375
EP - 379
JO - Paediatric Anaesthesia
JF - Paediatric Anaesthesia
IS - 4
ER -